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A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen-containing bisphosphonates.
Mönkkönen H, Auriola S, Lehenkari P, Kellinsalmi M, Hassinen IE, Vepsäläinen J, Mönkkönen J. Mönkkönen H, et al. Among authors: kellinsalmi m. Br J Pharmacol. 2006 Feb;147(4):437-45. doi: 10.1038/sj.bjp.0706628. Br J Pharmacol. 2006. PMID: 16402039 Free PMC article.