Kelly EJ - Search Results

1

Bioactivation of 4-Ipomeanol by a CYP4B enzyme in bovine lung and inhibition by HET0016.

Parkinson OT, Kelly EJ, Bezabih E, Whittington D, Rettie AE. Parkinson OT, et al. Among authors: kelly ej. J Vet Pharmacol Ther. 2012 Aug;35(4):402-5. doi: 10.1111/j.1365-2885.2011.01339.x. Epub 2011 Sep 15. J Vet Pharmacol Ther. 2012. PMID: 21919916 Free PMC article. No abstract available.

2

Purification and characterization of hexahistidine-tagged cyclohexanone monooxygenase expressed in Saccharomyces cerevisiae and Escherichia coli.

Cheesman MJ, Kneller MB, Kelly EJ, Thompson SJ, Yeung CK, Eaton DL, Rettie AE. Cheesman MJ, et al. Among authors: kelly ej. Protein Expr Purif. 2001 Feb;21(1):81-6. doi: 10.1006/prep.2000.1340. Protein Expr Purif. 2001. PMID: 11162390

3

Are we optimizing gestational diabetes treatment with glyburide? The pharmacologic basis for better clinical practice.

Hebert MF, Ma X, Naraharisetti SB, Krudys KM, Umans JG, Hankins GD, Caritis SN, Miodovnik M, Mattison DR, Unadkat JD, Kelly EJ, Blough D, Cobelli C, Ahmed MS, Snodgrass WR, Carr DB, Easterling TR, Vicini P; Obstetric-Fetal Pharmacology Research Unit Network. Hebert MF, et al. Among authors: kelly ej. Clin Pharmacol Ther. 2009 Jun;85(6):607-14. doi: 10.1038/clpt.2009.5. Epub 2009 Mar 18. Clin Pharmacol Ther. 2009. PMID: 19295505 Free PMC article. Clinical Trial.

4

Expression and characterization of CYP4V2 as a fatty acid omega-hydroxylase.

Nakano M, Kelly EJ, Rettie AE. Nakano M, et al. Among authors: kelly ej. Drug Metab Dispos. 2009 Nov;37(11):2119-22. doi: 10.1124/dmd.109.028530. Epub 2009 Aug 6. Drug Metab Dispos. 2009. PMID: 19661213 Free PMC article.

5

Finding homes for orphan cytochrome P450s: CYP4V2 and CYP4F22 in disease states.

Kelly EJ, Nakano M, Rohatgi P, Yarov-Yarovoy V, Rettie AE. Kelly EJ, et al. Mol Interv. 2011 Apr;11(2):124-32. doi: 10.1124/mi.11.2.10. Mol Interv. 2011. PMID: 21540472 Free PMC article. Review.

6

CYP4V2 in Bietti's crystalline dystrophy: ocular localization, metabolism of ω-3-polyunsaturated fatty acids, and functional deficit of the p.H331P variant.

Nakano M, Kelly EJ, Wiek C, Hanenberg H, Rettie AE. Nakano M, et al. Among authors: kelly ej. Mol Pharmacol. 2012 Oct;82(4):679-86. doi: 10.1124/mol.112.080085. Epub 2012 Jul 6. Mol Pharmacol. 2012. PMID: 22772592 Free PMC article.

7

Generation and characterization of a Cyp4b1 null mouse and the role of CYP4B1 in the activation and toxicity of Ipomeanol.

Parkinson OT, Liggitt HD, Rettie AE, Kelly EJ. Parkinson OT, et al. Among authors: kelly ej. Toxicol Sci. 2013 Aug;134(2):243-50. doi: 10.1093/toxsci/kft123. Epub 2013 Jun 7. Toxicol Sci. 2013. PMID: 23748241 Free PMC article.

8

Ocular cytochrome P450s and transporters: roles in disease and endobiotic and xenobiotic disposition.

Nakano M, Lockhart CM, Kelly EJ, Rettie AE. Nakano M, et al. Among authors: kelly ej. Drug Metab Rev. 2014 Aug;46(3):247-60. doi: 10.3109/03602532.2014.921190. Epub 2014 May 26. Drug Metab Rev. 2014. PMID: 24856391 Free PMC article. Review.

9

Generation and characterization of a murine model of Bietti crystalline dystrophy.

Lockhart CM, Nakano M, Rettie AE, Kelly EJ. Lockhart CM, et al. Among authors: kelly ej. Invest Ophthalmol Vis Sci. 2014 Aug 12;55(9):5572-81. doi: 10.1167/iovs.13-13717. Invest Ophthalmol Vis Sci. 2014. PMID: 25118264 Free PMC article.

10

Identification of amino acid determinants in CYP4B1 for optimal catalytic processing of 4-ipomeanol.

Wiek C, Schmidt EM, Roellecke K, Freund M, Nakano M, Kelly EJ, Kaisers W, Yarov-Yarovoy V, Kramm CM, Rettie AE, Hanenberg H. Wiek C, et al. Among authors: kelly ej. Biochem J. 2015 Jan 1;465(1):103-14. doi: 10.1042/BJ20140813. Biochem J. 2015. PMID: 25247810 Free PMC article.

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