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Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction.
Moy LY, Jia Y, Caniga M, Lieber G, Gil M, Fernandez X, Sirkowski E, Miller R, Alexander JP, Lee HH, Shin JD, Ellis JM, Chen H, Wilhelm A, Yu H, Vincent S, Chapman RW, Kelly N, Hickey E, Abraham WM, Northrup A, Miller T, Houshyar H, Crackower MA. Moy LY, et al. Among authors: kelly n. Am J Respir Cell Mol Biol. 2013 Dec;49(6):1085-92. doi: 10.1165/rcmb.2013-0200OC. Am J Respir Cell Mol Biol. 2013. PMID: 23889698
Mineralocorticoid receptor antagonists attenuate pulmonary inflammation and bleomycin-evoked fibrosis in rodent models.
Lieber GB, Fernandez X, Mingo GG, Jia Y, Caniga M, Gil MA, Keshwani S, Woodhouse JD, Cicmil M, Moy LY, Kelly N, Jimenez J, Crawley Y, Anthes JC, Klappenbach J, Ma YL, McLeod RL. Lieber GB, et al. Among authors: kelly n. Eur J Pharmacol. 2013 Oct 15;718(1-3):290-8. doi: 10.1016/j.ejphar.2013.08.019. Epub 2013 Sep 5. Eur J Pharmacol. 2013. PMID: 24012780
Overcoming mutagenicity and ion channel activity: optimization of selective spleen tyrosine kinase inhibitors.
Ellis JM, Altman MD, Bass A, Butcher JW, Byford AJ, Donofrio A, Galloway S, Haidle AM, Jewell J, Kelly N, Leccese EK, Lee S, Maddess M, Miller JR, Moy LY, Osimboni E, Otte RD, Reddy MV, Spencer K, Sun B, Vincent SH, Ward GJ, Woo GH, Yang C, Houshyar H, Northrup AB. Ellis JM, et al. Among authors: kelly n. J Med Chem. 2015 Feb 26;58(4):1929-39. doi: 10.1021/jm5018169. Epub 2015 Feb 16. J Med Chem. 2015. PMID: 25625541
The ClC-1 chloride channel inhibitor NMD670 improves skeletal muscle function in rat models and patients with myasthenia gravis.
Skov M, Ruijs TQ, Grønnebæk TS, Skals M, Riisager A, Winther JB, Dybdahl KLT, Findsen A, Morgen JJ, Huus N, Broch-Lips M, Nielsen OB, de Cuba CMKE, Heuberger JAAC, de Kam ML, Tannemaat M, Verschuuren JJGM, Knutsen LJS, Kelly NM, Jensen KG, Arnold WD, Burghes AH, Olesen C, Bold J, Petersen TK, Quiroz JA, Hutchison J, Chin ER, Groeneveld GJ, Pedersen TH. Skov M, et al. Among authors: kelly nm. Sci Transl Med. 2024 Mar 20;16(739):eadk9109. doi: 10.1126/scitranslmed.adk9109. Epub 2024 Mar 20. Sci Transl Med. 2024. PMID: 38507469 Clinical Trial.
687 results