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Structural investigation of CDCA3-Cdh1 protein-protein interactions using in vitro studies and molecular dynamics simulation.
Barbhuiya TK, Fisher M, Boittier ED, Bolderson E, O'Byrne KJ, Richard DJ, Adams MN, Gandhi NS. Barbhuiya TK, et al. Among authors: o byrne kj. Protein Sci. 2023 Mar;32(3):e4572. doi: 10.1002/pro.4572. Protein Sci. 2023. PMID: 36691744 Free PMC article.
CDCA3 is an intrinsically disordered protein and contains both C-terminal KEN box and D-box recognition motifs, enabling binding to Cdh1. ...We identified the role of H-bonds, hydrophobic and ionic interactions across the CDCA3 ABBA-like motif in the linker region between …
CDCA3 is an intrinsically disordered protein and contains both C-terminal KEN box and D-box recognition motifs, enabling binding to C …
Sequencing of therapy following first-line afatinib in patients with EGFR mutation-positive non-small cell lung cancer.
Park K, Bennouna J, Boyer M, Hida T, Hirsh V, Kato T, Lu S, Mok T, Nakagawa K, O'Byrne K, Paz-Ares L, Schuler M, Sibilot DM, Tan EH, Tanaka H, Wu YL, Yang JC, Zhang L, Zhou C, Märten A, Tang W, Yamamoto N. Park K, et al. Among authors: o byrne k. Lung Cancer. 2019 Jun;132:126-131. doi: 10.1016/j.lungcan.2019.04.014. Epub 2019 Apr 10. Lung Cancer. 2019. PMID: 31097085 Free article. Clinical Trial.
Towards a biological staging model for operable non-small cell lung cancer.
O'Byrne KJ, Cox G, Swinson D, Richardson D, Edwards JG, Lolljee J, Andi A, Koukourakis MI, Giatromanolaki A, Gatter K, Harris AL, Waller D, Jones JL. O'Byrne KJ, et al. Lung Cancer. 2001 Dec;34 Suppl 2:S83-9. doi: 10.1016/s0169-5002(01)00352-x. Lung Cancer. 2001. PMID: 11720747