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G protein-coupled receptor allosterism and complexing.
Christopoulos A, Kenakin T. Christopoulos A, et al. Pharmacol Rev. 2002 Jun;54(2):323-74. doi: 10.1124/pr.54.2.323. Pharmacol Rev. 2002. PMID: 12037145 Review.
Cellular assays as portals to seven-transmembrane receptor-based drug discovery.
Kenakin TP. Kenakin TP. Nat Rev Drug Discov. 2009 Aug;8(8):617-26. doi: 10.1038/nrd2838. Epub 2009 Jul 17. Nat Rev Drug Discov. 2009. PMID: 19609267 Review.
'7TM receptor allostery: putting numbers to shapeshifting proteins.
Kenakin TP. Kenakin TP. Trends Pharmacol Sci. 2009 Sep;30(9):460-9. doi: 10.1016/j.tips.2009.06.007. Epub 2009 Sep 2. Trends Pharmacol Sci. 2009. PMID: 19729207 Review.
Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor.
Nguyen T, Li JX, Thomas BF, Wiley JL, Kenakin TP, Zhang Y. Nguyen T, et al. Med Res Rev. 2017 May;37(3):441-474. doi: 10.1002/med.21418. Epub 2016 Nov 23. Med Res Rev. 2017. PMID: 27879006 Free PMC article. Review.
International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands.
Christopoulos A, Changeux JP, Catterall WA, Fabbro D, Burris TP, Cidlowski JA, Olsen RW, Peters JA, Neubig RR, Pin JP, Sexton PM, Kenakin TP, Ehlert FJ, Spedding M, Langmead CJ. Christopoulos A, et al. Pharmacol Rev. 2014 Oct;66(4):918-47. doi: 10.1124/pr.114.008862. Pharmacol Rev. 2014. PMID: 25026896
Refining efficacy: allosterism and bias in G protein-coupled receptor signaling.
Luttrell LM, Kenakin TP. Luttrell LM, et al. Methods Mol Biol. 2011;756:3-35. doi: 10.1007/978-1-61779-160-4_1. Methods Mol Biol. 2011. PMID: 21870218 Review.
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