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Long 3'UTRs predispose neurons to inflammation by promoting immunostimulatory double-stranded RNA formation.
Sci Immunol. 2023 Oct 27;8(88):eadg2979. doi: 10.1126/sciimmunol.adg2979. Epub 2023 Oct 20.
Sci Immunol. 2023.
PMID: 37862432
Free PMC article.
ADAR1 regulates dsRNA formation in nuclear and mitochondrial transcripts through editing-dependent and -independent mechanisms.
Shin H, Dorrity TJ, Aruda J, Wiegand KA, Nam JS, Yang J, Jones AS, Gertie JA, Singh MK, Yin Y, He K, Sarker R, Soni RK, Suh Y, Chio IIC, Rouskin S, Chung H.
Shin H, et al. Among authors: wiegand ka.
Cell Rep. 2026 Mar 24;45(3):117026. doi: 10.1016/j.celrep.2026.117026. Epub 2026 Mar 7.
Cell Rep. 2026.
PMID: 41800619
Free PMC article.
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