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Probiotic-guided CAR-T cells for solid tumor targeting.
Vincent RL, Gurbatri CR, Li F, Vardoshvili A, Coker C, Im J, Ballister ER, Rouanne M, Savage T, de Los Santos-Alexis K, Redenti A, Brockmann L, Komaranchath M, Arpaia N, Danino T. Vincent RL, et al. Among authors: de los santos alexis k. Science. 2023 Oct 13;382(6667):211-218. doi: 10.1126/science.add7034. Epub 2023 Oct 12. Science. 2023. PMID: 37824640 Free PMC article.
Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis.
Savage TM, Fortson KT, de Los Santos-Alexis K, Oliveras-Alsina A, Rouanne M, Rae SS, Gamarra JR, Shayya H, Kornberg A, Cavero R, Li F, Han A, Haeusler RA, Adam J, Schwabe RF, Arpaia N. Savage TM, et al. Among authors: de los santos alexis k. Immunity. 2024 Feb 13;57(2):303-318.e6. doi: 10.1016/j.immuni.2024.01.009. Epub 2024 Feb 2. Immunity. 2024. PMID: 38309273 Free PMC article.
Heparan sulfate regulates amphiregulin signaling towards reparative lung mesenchymal cells during influenza A infection.
Loffredo LF, Surpur A, Ringham OR, Li F, de Los Santos-Alexis K, Arpaia N. Loffredo LF, et al. Among authors: de los santos alexis k. bioRxiv [Preprint]. 2024 Apr 28:2024.04.25.591175. doi: 10.1101/2024.04.25.591175. bioRxiv. 2024. Update in: Nat Commun. 2025 Mar 3;16(1):2129. doi: 10.1038/s41467-025-57362-z. PMID: 38712053 Free PMC article. Updated. Preprint.