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Replication study and meta-analysis in European samples supports association of the 3p21.1 locus with bipolar disorder.
Vassos E, Steinberg S, Cichon S, Breen G, Sigurdsson E, Andreassen OA, Djurovic S, Morken G, Grigoroiu-Serbanescu M, Diaconu CC, Czerski PM, Hauser J, Babadjanova G, Abramova LI, Mühleisen TW, Nöthen MM, Rietschel M, McGuffin P, St Clair D, Gustafsson O, Melle I, Pietiläinen OP, Ruggeri M, Tosato S, Werge T, Ophoff RA; GROUP Consortium; Rujescu D, Børglum AD, Mors O, Mortensen PB, Demontis D, Hollegaard MV, van Winkel R, Kenis G, De Hert M, Réthelyi JM, Bitter I, Rubino IA, Golimbet V, Kiemeney LA, van den Berg LH, Franke B, Jönsson EG, Farmer A, Stefansson H, Stefansson K, Collier DA. Vassos E, et al. Among authors: kenis g. Biol Psychiatry. 2012 Oct 15;72(8):645-50. doi: 10.1016/j.biopsych.2012.02.040. Epub 2012 May 5. Biol Psychiatry. 2012. PMID: 22560537
No association between MTHFR C677T or A1298C and age at onset of schizophrenia.
Peerbooms O, Rutten BP, Decoster J, van Os J, Kenis G, De Hert M, van Winkel R. Peerbooms O, et al. Among authors: kenis g. Am J Med Genet B Neuropsychiatr Genet. 2010 Oct 5;153B(7):1362-3; author reply 1361. doi: 10.1002/ajmg.b.31114. Am J Med Genet B Neuropsychiatr Genet. 2010. PMID: 20593383 No abstract available.
Meta-analysis of MTHFR gene variants in schizophrenia, bipolar disorder and unipolar depressive disorder: evidence for a common genetic vulnerability?
Peerbooms OL, van Os J, Drukker M, Kenis G, Hoogveld L; MTHFR in Psychiatry Group; de Hert M, Delespaul P, van Winkel R, Rutten BP. Peerbooms OL, et al. Among authors: kenis g. Brain Behav Immun. 2011 Nov;25(8):1530-43. doi: 10.1016/j.bbi.2010.12.006. Epub 2010 Dec 24. Brain Behav Immun. 2011. PMID: 21185933 Review.
Common variants at VRK2 and TCF4 conferring risk of schizophrenia.
Steinberg S, de Jong S; Irish Schizophrenia Genomics Consortium; Andreassen OA, Werge T, Børglum AD, Mors O, Mortensen PB, Gustafsson O, Costas J, Pietiläinen OP, Demontis D, Papiol S, Huttenlocher J, Mattheisen M, Breuer R, Vassos E, Giegling I, Fraser G, Walker N, Tuulio-Henriksson A, Suvisaari J, Lönnqvist J, Paunio T, Agartz I, Melle I, Djurovic S, Strengman E; GROUP; Jürgens G, Glenthøj B, Terenius L, Hougaard DM, Ørntoft T, Wiuf C, Didriksen M, Hollegaard MV, Nordentoft M, van Winkel R, Kenis G, Abramova L, Kaleda V, Arrojo M, Sanjuán J, Arango C, Sperling S, Rossner M, Ribolsi M, Magni V, Siracusano A, Christiansen C, Kiemeney LA, Veldink J, van den Berg L, Ingason A, Muglia P, Murray R, Nöthen MM, Sigurdsson E, Petursson H, Thorsteinsdottir U, Kong A, Rubino IA, De Hert M, Réthelyi JM, Bitter I, Jönsson EG, Golimbet V, Carracedo A, Ehrenreich H, Craddock N, Owen MJ, O'Donovan MC; Wellcome Trust Case Control Consortium 2; Ruggeri M, Tosato S, Peltonen L, Ophoff RA, Collier DA, St Clair D, Rietschel M, Cichon S, Stefansson H, Rujescu D, Stefansson K. Steinberg S, et al. Among authors: kenis g. Hum Mol Genet. 2011 Oct 15;20(20):4076-81. doi: 10.1093/hmg/ddr325. Epub 2011 Jul 26. Hum Mol Genet. 2011. PMID: 21791550 Free PMC article.
Genome-wide association study identifies five new schizophrenia loci.
Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium. Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium. Nat Genet. 2011 Sep 18;43(10):969-76. doi: 10.1038/ng.940. Nat Genet. 2011. PMID: 21926974 Free PMC article.
Genetic schizophrenia risk variants jointly modulate total brain and white matter volume.
Terwisscha van Scheltinga AF, Bakker SC, van Haren NE, Derks EM, Buizer-Voskamp JE, Boos HB, Cahn W, Hulshoff Pol HE, Ripke S, Ophoff RA, Kahn RS; Psychiatric Genome-wide Association Study Consortium. Terwisscha van Scheltinga AF, et al. Biol Psychiatry. 2013 Mar 15;73(6):525-31. doi: 10.1016/j.biopsych.2012.08.017. Epub 2012 Oct 3. Biol Psychiatry. 2013. PMID: 23039932 Free PMC article.
All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs.
Schork AJ, Thompson WK, Pham P, Torkamani A, Roddey JC, Sullivan PF, Kelsoe JR, O'Donovan MC, Furberg H; Tobacco and Genetics Consortium; Bipolar Disorder Psychiatric Genomics Consortium; Schizophrenia Psychiatric Genomics Consortium; Schork NJ, Andreassen OA, Dale AM. Schork AJ, et al. PLoS Genet. 2013 Apr;9(4):e1003449. doi: 10.1371/journal.pgen.1003449. Epub 2013 Apr 25. PLoS Genet. 2013. PMID: 23637621 Free PMC article.
Impact of variation in the BDNF gene on social stress sensitivity and the buffering impact of positive emotions: replication and extension of a gene-environment interaction.
van Winkel M, Peeters F, van Winkel R, Kenis G, Collip D, Geschwind N, Jacobs N, Derom C, Thiery E, van Os J, Myin-Germeys I, Wichers M. van Winkel M, et al. Among authors: kenis g. Eur Neuropsychopharmacol. 2014 Jun;24(6):930-8. doi: 10.1016/j.euroneuro.2014.02.005. Epub 2014 Feb 18. Eur Neuropsychopharmacol. 2014. PMID: 24613654 Free article.
175 results