Kensler TW - Search Results

1

Loss of Nrf2 in mice evokes a congenital intrahepatic shunt that alters hepatic oxygen and protein expression gradients and toxicity.

Skoko JJ, Wakabayashi N, Noda K, Kimura S, Tobita K, Shigemura N, Tsujita T, Yamamoto M, Kensler TW. Skoko JJ, et al. Among authors: kensler tw. Toxicol Sci. 2014 Sep;141(1):112-9. doi: 10.1093/toxsci/kfu109. Epub 2014 Jun 12. Toxicol Sci. 2014. PMID: 24924401 Free PMC article.

2

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.

Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, Kensler TW. Ramos-Gomez M, et al. Among authors: kensler tw. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3410-5. doi: 10.1073/pnas.051618798. Proc Natl Acad Sci U S A. 2001. PMID: 11248092 Free PMC article.

3

Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione.

Kwak MK, Itoh K, Yamamoto M, Sutter TR, Kensler TW. Kwak MK, et al. Among authors: kensler tw. Mol Med. 2001 Feb;7(2):135-45. Mol Med. 2001. PMID: 11471548 Free PMC article.

4

Role of NRF2 in protection against hyperoxic lung injury in mice.

Cho HY, Jedlicka AE, Reddy SP, Kensler TW, Yamamoto M, Zhang LY, Kleeberger SR. Cho HY, et al. Among authors: kensler tw. Am J Respir Cell Mol Biol. 2002 Feb;26(2):175-82. doi: 10.1165/ajrcmb.26.2.4501. Am J Respir Cell Mol Biol. 2002. PMID: 11804867

5

Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter.

Kwak MK, Itoh K, Yamamoto M, Kensler TW. Kwak MK, et al. Among authors: kensler tw. Mol Cell Biol. 2002 May;22(9):2883-92. doi: 10.1128/MCB.22.9.2883-2892.2002. Mol Cell Biol. 2002. PMID: 11940647 Free PMC article.

6

Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.

Thimmulappa RK, Mai KH, Srisuma S, Kensler TW, Yamamoto M, Biswal S. Thimmulappa RK, et al. Among authors: kensler tw. Cancer Res. 2002 Sep 15;62(18):5196-203. Cancer Res. 2002. PMID: 12234984

7

Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.

Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW. Kwak MK, et al. Among authors: kensler tw. J Biol Chem. 2003 Mar 7;278(10):8135-45. doi: 10.1074/jbc.M211898200. Epub 2002 Dec 27. J Biol Chem. 2003. PMID: 12506115 Free article.

8

Interactive effects of nrf2 genotype and oltipraz on benzo[a]pyrene-DNA adducts and tumor yield in mice.

Ramos-Gomez M, Dolan PM, Itoh K, Yamamoto M, Kensler TW. Ramos-Gomez M, et al. Among authors: kensler tw. Carcinogenesis. 2003 Mar;24(3):461-7. doi: 10.1093/carcin/24.3.461. Carcinogenesis. 2003. PMID: 12663505

9

Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway.

Kwak MK, Wakabayashi N, Greenlaw JL, Yamamoto M, Kensler TW. Kwak MK, et al. Among authors: kensler tw. Mol Cell Biol. 2003 Dec;23(23):8786-94. doi: 10.1128/MCB.23.23.8786-8794.2003. Mol Cell Biol. 2003. PMID: 14612418 Free PMC article.

10

Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers.

Wakabayashi N, Dinkova-Kostova AT, Holtzclaw WD, Kang MI, Kobayashi A, Yamamoto M, Kensler TW, Talalay P. Wakabayashi N, et al. Among authors: kensler tw. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):2040-5. doi: 10.1073/pnas.0307301101. Epub 2004 Feb 5. Proc Natl Acad Sci U S A. 2004. PMID: 14764894 Free PMC article.

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