Kent DG - Search Results

1

The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress.

van Galen P, Kreso A, Mbong N, Kent DG, Fitzmaurice T, Chambers JE, Xie S, Laurenti E, Hermans K, Eppert K, Marciniak SJ, Goodall JC, Green AR, Wouters BG, Wienholds E, Dick JE. van Galen P, et al. Among authors: kent dg. Nature. 2014 Jun 12;510(7504):268-72. doi: 10.1038/nature13228. Epub 2014 Apr 28. Nature. 2014. PMID: 24776803

2

Mouse models of myeloproliferative neoplasms: JAK of all grades.

Li J, Kent DG, Chen E, Green AR. Li J, et al. Among authors: kent dg. Dis Model Mech. 2011 May;4(3):311-7. doi: 10.1242/dmm.006817. Dis Model Mech. 2011. PMID: 21558064 Free PMC article. Review.

3

Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion.

Kent DG, Li J, Tanna H, Fink J, Kirschner K, Pask DC, Silber Y, Hamilton TL, Sneade R, Simons BD, Green AR. Kent DG, et al. PLoS Biol. 2013;11(6):e1001576. doi: 10.1371/journal.pbio.1001576. Epub 2013 Jun 4. PLoS Biol. 2013. PMID: 23750118 Free PMC article.

4

The Lin28b-let-7-Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells.

Copley MR, Babovic S, Benz C, Knapp DJ, Beer PA, Kent DG, Wohrer S, Treloar DQ, Day C, Rowe K, Mader H, Kuchenbauer F, Humphries RK, Eaves CJ. Copley MR, et al. Among authors: kent dg. Nat Cell Biol. 2013 Aug;15(8):916-25. doi: 10.1038/ncb2783. Epub 2013 Jun 30. Nat Cell Biol. 2013. PMID: 23811688

5

JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease.

Li J, Kent DG, Godfrey AL, Manning H, Nangalia J, Aziz A, Chen E, Saeb-Parsy K, Fink J, Sneade R, Hamilton TL, Pask DC, Silber Y, Zhao X, Ghevaert C, Liu P, Green AR. Li J, et al. Among authors: kent dg. Blood. 2014 May 15;123(20):3139-51. doi: 10.1182/blood-2013-06-510222. Epub 2014 Apr 1. Blood. 2014. PMID: 24692758 Free article.

6

Clonal heterogeneity as a driver of disease variability in the evolution of myeloproliferative neoplasms.

Prick J, de Haan G, Green AR, Kent DG. Prick J, et al. Among authors: kent dg. Exp Hematol. 2014 Oct;42(10):841-51. doi: 10.1016/j.exphem.2014.07.268. Epub 2014 Sep 6. Exp Hematol. 2014. PMID: 25201757 Free article. Review.

7

Nongenetic stochastic expansion of JAK2V617F-homozygous subclones in polycythemia vera?

Godfrey AL, Nangalia J, Baxter EJ, Massie CE, Kent DG, Papaemmanuil E, Campbell PJ, Green AR. Godfrey AL, et al. Among authors: kent dg. Blood. 2014 Nov 20;124(22):3332-4. doi: 10.1182/blood-2014-09-603043. Blood. 2014. PMID: 25414437 Free PMC article. No abstract available.

8

Effect of mutation order on myeloproliferative neoplasms.

Ortmann CA, Kent DG, Nangalia J, Silber Y, Wedge DC, Grinfeld J, Baxter EJ, Massie CE, Papaemmanuil E, Menon S, Godfrey AL, Dimitropoulou D, Guglielmelli P, Bellosillo B, Besses C, Döhner K, Harrison CN, Vassiliou GS, Vannucchi A, Campbell PJ, Green AR. Ortmann CA, et al. Among authors: kent dg. N Engl J Med. 2015 Feb 12;372(7):601-612. doi: 10.1056/NEJMoa1412098. N Engl J Med. 2015. PMID: 25671252 Free PMC article.

9

Effect of mutation order on myeloproliferative neoplasms.

Kent DG, Ortmann CA, Green AR. Kent DG, et al. N Engl J Med. 2015 May 7;372(19):1865-6. doi: 10.1056/NEJMc1503143. N Engl J Med. 2015. PMID: 25946289 No abstract available.

10

Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations.

Wilson NK, Kent DG, Buettner F, Shehata M, Macaulay IC, Calero-Nieto FJ, Sánchez Castillo M, Oedekoven CA, Diamanti E, Schulte R, Ponting CP, Voet T, Caldas C, Stingl J, Green AR, Theis FJ, Göttgens B. Wilson NK, et al. Among authors: kent dg. Cell Stem Cell. 2015 Jun 4;16(6):712-24. doi: 10.1016/j.stem.2015.04.004. Epub 2015 May 21. Cell Stem Cell. 2015. PMID: 26004780 Free PMC article.

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