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A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes.
Kent OA, Mendell JT. Kent OA, et al. Oncogene. 2006 Oct 9;25(46):6188-96. doi: 10.1038/sj.onc.1209913. Oncogene. 2006. PMID: 17028598 Review.
Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice.
Pramanik D, Campbell NR, Karikari C, Chivukula R, Kent OA, Mendell JT, Maitra A. Pramanik D, et al. Among authors: kent oa. Mol Cancer Ther. 2011 Aug;10(8):1470-80. doi: 10.1158/1535-7163.MCT-11-0152. Epub 2011 May 27. Mol Cancer Ther. 2011. PMID: 21622730 Free PMC article.
Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway.
Kent OA, Chivukula RR, Mullendore M, Wentzel EA, Feldmann G, Lee KH, Liu S, Leach SD, Maitra A, Mendell JT. Kent OA, et al. Genes Dev. 2010 Dec 15;24(24):2754-9. doi: 10.1101/gad.1950610. Genes Dev. 2010. PMID: 21159816 Free PMC article.
Identifying targets of miR-143 using a SILAC-based proteomic approach.
Yang Y, Chaerkady R, Kandasamy K, Huang TC, Selvan LD, Dwivedi SB, Kent OA, Mendell JT, Pandey A. Yang Y, et al. Among authors: kent oa. Mol Biosyst. 2010 Oct;6(10):1873-82. doi: 10.1039/c004401f. Epub 2010 Jun 14. Mol Biosyst. 2010. PMID: 20544124 Free PMC article.
A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells.
Kent OA, Mullendore M, Wentzel EA, López-Romero P, Tan AC, Alvarez H, West K, Ochs MF, Hidalgo M, Arking DE, Maitra A, Mendell JT. Kent OA, et al. Cancer Biol Ther. 2009 Nov;8(21):2013-24. doi: 10.4161/cbt.8.21.9685. Cancer Biol Ther. 2009. PMID: 20037478 Free PMC article.
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis.
Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH, Feldmann G, Yamakuchi M, Ferlito M, Lowenstein CJ, Arking DE, Beer MA, Maitra A, Mendell JT. Chang TC, et al. Among authors: kent oa. Mol Cell. 2007 Jun 8;26(5):745-52. doi: 10.1016/j.molcel.2007.05.010. Epub 2007 May 31. Mol Cell. 2007. PMID: 17540599 Free PMC article.
Functional integration of microRNAs into oncogenic and tumor suppressor pathways.
Lotterman CD, Kent OA, Mendell JT. Lotterman CD, et al. Among authors: kent oa. Cell Cycle. 2008 Aug 15;7(16):2493-9. doi: 10.4161/cc.7.16.6452. Epub 2008 Aug 17. Cell Cycle. 2008. PMID: 18719378 Free PMC article.
In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge.
Kent OA, Steenbergen C, Das S. Kent OA, et al. J Vis Exp. 2018 Jun 15;(136):57845. doi: 10.3791/57845. J Vis Exp. 2018. PMID: 29985373 Free PMC article.
Nuclear miRNA regulates the mitochondrial genome in the heart.
Das S, Ferlito M, Kent OA, Fox-Talbot K, Wang R, Liu D, Raghavachari N, Yang Y, Wheelan SJ, Murphy E, Steenbergen C. Das S, et al. Among authors: kent oa. Circ Res. 2012 Jun 8;110(12):1596-603. doi: 10.1161/CIRCRESAHA.112.267732. Epub 2012 Apr 19. Circ Res. 2012. PMID: 22518031 Free PMC article.
Divergent Effects of miR-181 Family Members on Myocardial Function Through Protective Cytosolic and Detrimental Mitochondrial microRNA Targets.
Das S, Kohr M, Dunkerly-Eyring B, Lee DI, Bedja D, Kent OA, Leung AK, Henao-Mejia J, Flavell RA, Steenbergen C. Das S, et al. Among authors: kent oa. J Am Heart Assoc. 2017 Feb 27;6(3):e004694. doi: 10.1161/JAHA.116.004694. J Am Heart Assoc. 2017. PMID: 28242633 Free PMC article.
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