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Human blood vessel organoids as a model of diabetic vasculopathy.
Wimmer RA, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, Taubenschmid J, Hämmerle M, Esk C, Bagley JA, Lindenhofer D, Chen G, Boehm M, Agu CA, Yang F, Fu B, Zuber J, Knoblich JA, Kerjaschki D, Penninger JM. Wimmer RA, et al. Among authors: Kerjaschki D. Nature. 2019 Jan;565(7740):505-510. doi: 10.1038/s41586-018-0858-8. Epub 2019 Jan 16. Nature. 2019. PMID: 30651639
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism.
Machnik A, Neuhofer W, Jantsch J, Dahlmann A, Tammela T, Machura K, Park JK, Beck FX, Müller DN, Derer W, Goss J, Ziomber A, Dietsch P, Wagner H, van Rooijen N, Kurtz A, Hilgers KF, Alitalo K, Eckardt KU, Luft FC, Kerjaschki D, Titze J. Machnik A, et al. Among authors: Kerjaschki D. Nat Med. 2009 May;15(5):545-52. doi: 10.1038/nm.1960. Epub 2009 May 3. Nat Med. 2009. PMID: 19412173
Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis.
Petrova TV, Karpanen T, Norrmén C, Mellor R, Tamakoshi T, Finegold D, Ferrell R, Kerjaschki D, Mortimer P, Ylä-Herttuala S, Miura N, Alitalo K. Petrova TV, et al. Among authors: Kerjaschki D. Nat Med. 2004 Sep;10(9):974-81. doi: 10.1038/nm1094. Epub 2004 Aug 22. Nat Med. 2004. PMID: 15322537
A previously unknown dermal blood vessel phenotype in skin inflammation.
Gröger M, Niederleithner H, Kerjaschki D, Petzelbauer P. Gröger M, et al. Among authors: Kerjaschki D. J Invest Dermatol. 2007 Dec;127(12):2893-900. doi: 10.1038/sj.jid.5701031. Epub 2007 Sep 20. J Invest Dermatol. 2007. PMID: 17882274
Enhanced lymph vessel density, remodeling, and inflammation are reflected by gene expression signatures in dermal lymphatic endothelial cells in type 2 diabetes.
Haemmerle M, Keller T, Egger G, Schachner H, Steiner CW, Stokic D, Neumayer C, Brown MK, Kerjaschki D, Hantusch B. Haemmerle M, et al. Among authors: Kerjaschki D. Diabetes. 2013 Jul;62(7):2509-29. doi: 10.2337/db12-0844. Epub 2013 Feb 19. Diabetes. 2013. PMID: 23423575 Free PMC article.
Lymphatic exosomes promote dendritic cell migration along guidance cues.
Brown M, Johnson LA, Leone DA, Majek P, Vaahtomeri K, Senfter D, Bukosza N, Schachner H, Asfour G, Langer B, Hauschild R, Parapatics K, Hong YK, Bennett KL, Kain R, Detmar M, Sixt M, Jackson DG, Kerjaschki D. Brown M, et al. Among authors: Kerjaschki D. J Cell Biol. 2018 Jun 4;217(6):2205-2221. doi: 10.1083/jcb.201612051. Epub 2018 Apr 12. J Cell Biol. 2018. PMID: 29650776 Free PMC article.
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes.
Leithner A, Eichner A, Müller J, Reversat A, Brown M, Schwarz J, Merrin J, de Gorter DJ, Schur F, Bayerl J, de Vries I, Wieser S, Hauschild R, Lai FP, Moser M, Kerjaschki D, Rottner K, Small JV, Stradal TE, Sixt M. Leithner A, et al. Among authors: Kerjaschki D. Nat Cell Biol. 2016 Nov;18(11):1253-1259. doi: 10.1038/ncb3426. Epub 2016 Oct 24. Nat Cell Biol. 2016. PMID: 27775702
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.
Martins R, Maier J, Gorki AD, Huber KV, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger MC, Radic-Sarikas B, Lardeau CH, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth SC, Decker T, Bennett KL, Kubicek S, Sixt M, Superti-Furga G, Knapp S. Martins R, et al. Among authors: Kerjaschki D. Nat Immunol. 2016 Dec;17(12):1361-1372. doi: 10.1038/ni.3590. Epub 2016 Oct 31. Nat Immunol. 2016. PMID: 27798618
Lymphatic precollectors contain a novel, specialized subpopulation of podoplanin low, CCL27-expressing lymphatic endothelial cells.
Wick N, Haluza D, Gurnhofer E, Raab I, Kasimir MT, Prinz M, Steiner CW, Reinisch C, Howorka A, Giovanoli P, Buchsbaum S, Krieger S, Tschachler E, Petzelbauer P, Kerjaschki D. Wick N, et al. Among authors: Kerjaschki D. Am J Pathol. 2008 Oct;173(4):1202-9. doi: 10.2353/ajpath.2008.080101. Epub 2008 Sep 4. Am J Pathol. 2008. PMID: 18772332 Free PMC article.
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