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Nitroreductase: a prodrug-activating enzyme for cancer gene therapy.
Searle PF, Chen MJ, Hu L, Race PR, Lovering AL, Grove JI, Guise C, Jaberipour M, James ND, Mautner V, Young LS, Kerr DJ, Mountain A, White SA, Hyde EI. Searle PF, et al. Among authors: kerr dj. Clin Exp Pharmacol Physiol. 2004 Nov;31(11):811-6. doi: 10.1111/j.1440-1681.2004.04085.x. Clin Exp Pharmacol Physiol. 2004. PMID: 15566399 Review.
Sensitization of colorectal and pancreatic cancer cell lines to the prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954) by retroviral transduction and expression of the E. coli nitroreductase gene.
Green NK, Youngs DJ, Neoptolemos JP, Friedlos F, Knox RJ, Springer CJ, Anlezark GM, Michael NP, Melton RG, Ford MJ, Young LS, Kerr DJ, Searle PF. Green NK, et al. Among authors: kerr dj. Cancer Gene Ther. 1997 Jul-Aug;4(4):229-38. Cancer Gene Ther. 1997. PMID: 9253508
350 results