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Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis.
Castillo-Quan JI, Li L, Kinghorn KJ, Ivanov DK, Tain LS, Slack C, Kerr F, Nespital T, Thornton J, Hardy J, Bjedov I, Partridge L. Castillo-Quan JI, et al. Among authors: kerr f. Cell Rep. 2016 Apr 19;15(3):638-650. doi: 10.1016/j.celrep.2016.03.041. Epub 2016 Apr 7. Cell Rep. 2016. PMID: 27068460 Free PMC article.
Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer's disease.
Kerr F, Sofola-Adesakin O, Ivanov DK, Gatliff J, Gomez Perez-Nievas B, Bertrand HC, Martinez P, Callard R, Snoeren I, Cochemé HM, Adcott J, Khericha M, Castillo-Quan JI, Wells G, Noble W, Thornton J, Partridge L. Kerr F, et al. PLoS Genet. 2017 Mar 2;13(3):e1006593. doi: 10.1371/journal.pgen.1006593. eCollection 2017 Mar. PLoS Genet. 2017. PMID: 28253260 Free PMC article.
Ageing increases vulnerability to aβ42 toxicity in Drosophila.
Rogers I, Kerr F, Martinez P, Hardy J, Lovestone S, Partridge L. Rogers I, et al. Among authors: kerr f. PLoS One. 2012;7(7):e40569. doi: 10.1371/journal.pone.0040569. Epub 2012 Jul 12. PLoS One. 2012. PMID: 22808195 Free PMC article.
Increased Glucose Transport into Neurons Rescues Aβ Toxicity in Drosophila.
Niccoli T, Cabecinha M, Tillmann A, Kerr F, Wong CT, Cardenes D, Vincent AJ, Bettedi L, Li L, Grönke S, Dols J, Partridge L. Niccoli T, et al. Among authors: kerr f. Curr Biol. 2016 Sep 12;26(17):2291-300. doi: 10.1016/j.cub.2016.07.017. Epub 2016 Aug 11. Curr Biol. 2016. PMID: 27524482 Free PMC article.
Deletion of endogenous Tau proteins is not detrimental in Drosophila.
Burnouf S, Grönke S, Augustin H, Dols J, Gorsky MK, Werner J, Kerr F, Alic N, Martinez P, Partridge L. Burnouf S, et al. Among authors: kerr f. Sci Rep. 2016 Mar 15;6:23102. doi: 10.1038/srep23102. Sci Rep. 2016. PMID: 26976084 Free PMC article.
193 results