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Vascular endothelial growth factor and vascular homeostasis.
Lazarus A, Keshet E. Lazarus A, et al. Proc Am Thorac Soc. 2011 Nov;8(6):508-11. doi: 10.1513/pats.201102-021MW. Proc Am Thorac Soc. 2011. PMID: 22052928 Review.
VEGF is required for dendritogenesis of newly born olfactory bulb interneurons.
Licht T, Eavri R, Goshen I, Shlomai Y, Mizrahi A, Keshet E. Licht T, et al. Development. 2010 Jan;137(2):261-71. doi: 10.1242/dev.039636. Development. 2010. PMID: 20040492
A transgenic platform for testing drugs intended for reversal of cardiac remodeling identifies a novel 11βHSD1 inhibitor rescuing hypertrophy independently of re-vascularization.
Gordon O, He Z, Gilon D, Gruener S, Pietranico-Cole S, Oppenheim A, Keshet E. Gordon O, et al. PLoS One. 2014 Mar 25;9(3):e92869. doi: 10.1371/journal.pone.0092869. eCollection 2014. PLoS One. 2014. PMID: 24667808 Free PMC article.
Vascular endothelial growth factor-induced neovascularization rescues cardiac function but not adverse remodeling at advanced ischemic heart disease.
Gordon O, Gilon D, He Z, May D, Lazarus A, Oppenheim A, Keshet E. Gordon O, et al. Arterioscler Thromb Vasc Biol. 2012 Jul;32(7):1642-51. doi: 10.1161/ATVBAHA.112.248674. Epub 2012 Apr 26. Arterioscler Thromb Vasc Biol. 2012. PMID: 22539593
A transgenic model for conditional induction and rescue of portal hypertension reveals a role of VEGF-mediated regulation of sinusoidal fenestrations.
May D, Djonov V, Zamir G, Bala M, Safadi R, Sklair-Levy M, Keshet E. May D, et al. PLoS One. 2011;6(7):e21478. doi: 10.1371/journal.pone.0021478. Epub 2011 Jul 11. PLoS One. 2011. PMID: 21779329 Free PMC article.
VEGF blockade results in sinusoidal endothelial cells (SECs) fenestrations closure and in accumulation and transformation of the normally quiescent hepatic stellate cells, i.e. provoking the two processes underlying sinusoidal capillarization. ...
VEGF blockade results in sinusoidal endothelial cells (SECs) fenestrations closure and in accumulation and transformation of the normally qu …
Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice.
Compernolle V, Brusselmans K, Acker T, Hoet P, Tjwa M, Beck H, Plaisance S, Dor Y, Keshet E, Lupu F, Nemery B, Dewerchin M, Van Veldhoven P, Plate K, Moons L, Collen D, Carmeliet P. Compernolle V, et al. Nat Med. 2002 Jul;8(7):702-10. doi: 10.1038/nm721. Epub 2002 Jun 10. Nat Med. 2002. PMID: 12053176
Decidual NK cells regulate key developmental processes at the human fetal-maternal interface.
Hanna J, Goldman-Wohl D, Hamani Y, Avraham I, Greenfield C, Natanson-Yaron S, Prus D, Cohen-Daniel L, Arnon TI, Manaster I, Gazit R, Yutkin V, Benharroch D, Porgador A, Keshet E, Yagel S, Mandelboim O. Hanna J, et al. Nat Med. 2006 Sep;12(9):1065-74. doi: 10.1038/nm1452. Epub 2006 Aug 6. Nat Med. 2006. PMID: 16892062
The vascular niche in adult neurogenesis.
Licht T, Keshet E. Licht T, et al. Mech Dev. 2015 Nov;138 Pt 1:56-62. doi: 10.1016/j.mod.2015.06.001. Epub 2015 Jun 20. Mech Dev. 2015. PMID: 26103548 Review.
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