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Vav1 and PI3K are required for phagocytosis of beta-glucan and subsequent superoxide generation by microglia.
Shah VB, Ozment-Skelton TR, Williams DL, Keshvara L. Shah VB, et al. Among authors: keshvara l. Mol Immunol. 2009 May;46(8-9):1845-53. doi: 10.1016/j.molimm.2009.01.014. Epub 2009 Feb 20. Mol Immunol. 2009. PMID: 19232731
beta-Glucan attenuates TLR2- and TLR4-mediated cytokine production by microglia.
Shah VB, Williams DL, Keshvara L. Shah VB, et al. Among authors: keshvara l. Neurosci Lett. 2009 Jul 24;458(3):111-5. doi: 10.1016/j.neulet.2009.04.039. Epub 2009 Apr 23. Neurosci Lett. 2009. PMID: 19393720 Free PMC article.
Beta-glucan activates microglia without inducing cytokine production in Dectin-1-dependent manner.
Shah VB, Huang Y, Keshwara R, Ozment-Skelton T, Williams DL, Keshvara L. Shah VB, et al. Among authors: keshvara l. J Immunol. 2008 Mar 1;180(5):2777-85. doi: 10.4049/jimmunol.180.5.2777. J Immunol. 2008. PMID: 18292498 Free article.
Tyrosine phosphorylated Disabled 1 recruits Crk family adapter proteins.
Huang Y, Magdaleno S, Hopkins R, Slaughter C, Curran T, Keshvara L. Huang Y, et al. Among authors: keshvara l. Biochem Biophys Res Commun. 2004 May 21;318(1):204-12. doi: 10.1016/j.bbrc.2004.04.023. Biochem Biophys Res Commun. 2004. PMID: 15110774
Signaling through Disabled 1 requires phosphoinositide binding.
Huang Y, Shah V, Liu T, Keshvara L. Huang Y, et al. Among authors: keshvara l. Biochem Biophys Res Commun. 2005 Jun 17;331(4):1460-8. doi: 10.1016/j.bbrc.2005.04.064. Biochem Biophys Res Commun. 2005. PMID: 15883038
Inhibition of signaling through the B cell antigen receptor by the protooncogene product, c-Cbl, requires Syk tyrosine 317 and the c-Cbl phosphotyrosine-binding domain.
Yankee TM, Keshvara LM, Sawasdikosol S, Harrison ML, Geahlen RL. Yankee TM, et al. Among authors: keshvara lm. J Immunol. 1999 Dec 1;163(11):5827-35. J Immunol. 1999. PMID: 10570266
Phosphorylation- and activation-independent association of the tyrosine kinase Syk and the tyrosine kinase substrates Cbl and Vav with tubulin in B-cells.
Fernandez JA, Keshvara LM, Peters JD, Furlong MT, Harrison ML, Geahlen RL. Fernandez JA, et al. Among authors: keshvara lm. J Biol Chem. 1999 Jan 15;274(3):1401-6. doi: 10.1074/jbc.274.3.1401. J Biol Chem. 1999. PMID: 9880513
Syk activation and dissociation from the B-cell antigen receptor is mediated by phosphorylation of tyrosine 130.
Keshvara LM, Isaacson C, Harrison ML, Geahlen RL. Keshvara LM, et al. J Biol Chem. 1997 Apr 18;272(16):10377-81. doi: 10.1074/jbc.272.16.10377. J Biol Chem. 1997. PMID: 9099676
Interaction of Disabled-1 and the GTPase activating protein Dab2IP in mouse brain.
Homayouni R, Magdaleno S, Keshvara L, Rice DS, Curran T. Homayouni R, et al. Among authors: keshvara l. Brain Res Mol Brain Res. 2003 Jul 23;115(2):121-9. doi: 10.1016/s0169-328x(03)00176-1. Brain Res Mol Brain Res. 2003. PMID: 12877983
Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling.
Keshvara L, Magdaleno S, Benhayon D, Curran T. Keshvara L, et al. J Neurosci. 2002 Jun 15;22(12):4869-77. doi: 10.1523/JNEUROSCI.22-12-04869.2002. J Neurosci. 2002. PMID: 12077184 Free PMC article.
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