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Page 1
Showing results for ketone ester health
Your search for Keytone Ester Health retrieved no results
A beta-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites.
Moya-Garzon MD, Wang M, Li VL, Lyu X, Wei W, Tung AS, Raun SH, Zhao M, Coassolo L, Islam H, Oliveira B, Dai Y, Spaas J, Delgado-Gonzalez A, Donoso K, Alvarez-Buylla A, Franco-Montalban F, Letian A, Ward CP, Liu L, Svensson KJ, Goldberg EL, Gardner CD, Little JP, Banik SM, Xu Y, Long JZ. Moya-Garzon MD, et al. Cell. 2025 Jan 9;188(1):175-186.e20. doi: 10.1016/j.cell.2024.10.032. Epub 2024 Nov 12. Cell. 2025. PMID: 39536746 Free PMC article.
Conversely, CNDP2-KO mice exhibit increased food intake and body weight following exogenous ketone ester supplementation or a ketogenic diet. CNDP2-dependent amino acid BHB-ylation and BHB-amino acid metabolites are also conserved in humans. Therefore, enzymatic ami …
Conversely, CNDP2-KO mice exhibit increased food intake and body weight following exogenous ketone ester supplementation or a …
Exogenous Ketone Supplements in Athletic Contexts: Past, Present, and Future.
Evans M, McClure TS, Koutnik AP, Egan B. Evans M, et al. Sports Med. 2022 Dec;52(Suppl 1):25-67. doi: 10.1007/s40279-022-01756-2. Epub 2022 Oct 10. Sports Med. 2022. PMID: 36214993 Free PMC article. Review.
There has been long-standing interest in the development of ingestible forms of ketone bodies that has recently resulted in the commercial availability of exogenous ketone supplements (EKS). These supplements in the form of ketone salts and ketone e …
There has been long-standing interest in the development of ingestible forms of ketone bodies that has recently resulted in the comme …
Ketone ester-enriched diet ameliorates motor and dopamine release deficits in MitoPark mice.
Mahajan VR, Nadel JA, King MT, Pawlosky RJ, Davis MI, Veech RL, Lovinger DM, Salinas AG. Mahajan VR, et al. Eur J Neurosci. 2024 Dec;60(11):6875-6890. doi: 10.1111/ejn.16601. Epub 2024 Nov 11. Eur J Neurosci. 2024. PMID: 39528410 Free PMC article.
Thus, we hypothesized that administration of a ketone ester-enriched diet (KEED) would improve motor and dopamine release deficits in MP mice. ...While the KEED did not preserve dopamine neurons or striatal dopamine axons, dopamine release in ketone diet MP m …
Thus, we hypothesized that administration of a ketone ester-enriched diet (KEED) would improve motor and dopamine release defi …
Metabolism of ketone bodies during exercise and training: physiological basis for exogenous supplementation.
Evans M, Cogan KE, Egan B. Evans M, et al. J Physiol. 2017 May 1;595(9):2857-2871. doi: 10.1113/JP273185. Epub 2016 Dec 7. J Physiol. 2017. PMID: 27861911 Free PMC article. Review.
Ketone bodies are oxidised as a fuel source during exercise, are markedly elevated during the post-exercise recovery period, and the ability to utilise ketone bodies is higher in exercise-trained skeletal muscle. ...Recent development of ketone esters …
Ketone bodies are oxidised as a fuel source during exercise, are markedly elevated during the post-exercise recovery period, and the …
Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes.
Cox PJ, Kirk T, Ashmore T, Willerton K, Evans R, Smith A, Murray AJ, Stubbs B, West J, McLure SW, King MT, Dodd MS, Holloway C, Neubauer S, Drawer S, Veech RL, Griffin JL, Clarke K. Cox PJ, et al. Cell Metab. 2016 Aug 9;24(2):256-68. doi: 10.1016/j.cmet.2016.07.010. Epub 2016 Jul 27. Cell Metab. 2016. PMID: 27475046 Free article. Clinical Trial.
Thus, we studied the biochemical advantages of ketosis in humans using a ketone ester-based form of nutrition without the unwanted milieu of endogenous ketone body production by caloric or carbohydrate restriction. ...These findings may hold clues to greater …
Thus, we studied the biochemical advantages of ketosis in humans using a ketone ester-based form of nutrition without the unwa …
Effect of weight-maintaining ketogenic diet on glycemic control and insulin sensitivity in obese T2D subjects.
Merovci A, Finley B, Hansis-Diarte A, Neppala S, Abdul-Ghani MA, Cersosimo E, Triplitt C, DeFronzo RA. Merovci A, et al. BMJ Open Diabetes Res Care. 2024 Oct 18;12(5):e004199. doi: 10.1136/bmjdrc-2024-004199. BMJ Open Diabetes Res Care. 2024. PMID: 39424350 Free PMC article. Clinical Trial.
RESEARCH DESIGN AND METHODS: 29 overweight obese subjects were randomized to one of three dietary interventions for 10 days: (1) Weight-maintaining standard diet; (2) Weight-maintaining ketogenic diet; (3) Weight-maintaining ketogenic diet plus supplementation with the ketone …
RESEARCH DESIGN AND METHODS: 29 overweight obese subjects were randomized to one of three dietary interventions for 10 days: (1) Weight-main …
Randomized Crossover Trial of 2-Week Ketone Ester Treatment in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction.
Gopalasingam N, Berg-Hansen K, Christensen KH, Ladefoged BT, Poulsen SH, Andersen MJ, Borlaug BA, Nielsen R, Møller N, Wiggers H. Gopalasingam N, et al. Circulation. 2024 Nov 12;150(20):1570-1583. doi: 10.1161/CIRCULATIONAHA.124.069732. Epub 2024 Aug 20. Circulation. 2024. PMID: 39162035 Clinical Trial.
Acute increases in circulating levels of ketone body 3-hydroxybutyrate have beneficial acute hemodynamic effects in patients without T2D with chronic heart failure with reduced ejection fraction. However, the cardiovascular effects of prolonged oral ketone ester …
Acute increases in circulating levels of ketone body 3-hydroxybutyrate have beneficial acute hemodynamic effects in patients without …
11C-Fixation Techniques.
Murrell E, Lindberg A, Garcia A, Vasdev N. Murrell E, et al. Methods Mol Biol. 2024;2729:3-13. doi: 10.1007/978-1-0716-3499-8_1. Methods Mol Biol. 2024. PMID: 38006487
Such procedures are widely applicable to numerous small molecules to form (11)C-labeled carboxylic acids, amides, esters, ketones, oxazolidinones, carbamates, and ureas. The steps for (11)C-fixation techniques described herein are tailored for a commercial automated …
Such procedures are widely applicable to numerous small molecules to form (11)C-labeled carboxylic acids, amides, esters, ketones …
Cardiovascular Effects of Oral Ketone Ester Treatment in Patients With Heart Failure With Reduced Ejection Fraction: A Randomized, Controlled, Double-Blind Trial.
Berg-Hansen K, Gopalasingam N, Christensen KH, Ladefoged B, Andersen MJ, Poulsen SH, Borlaug BA, Nielsen R, Møller N, Wiggers H. Berg-Hansen K, et al. Circulation. 2024 May 7;149(19):1474-1489. doi: 10.1161/CIRCULATIONAHA.123.067971. Epub 2024 Mar 27. Circulation. 2024. PMID: 38533643 Free PMC article. Clinical Trial.
BACKGROUND: Heart failure triggers a shift in myocardial metabolic substrate utilization, favoring the ketone body 3-hydroxybutyrate as energy source. We hypothesized that 14-day treatment with ketone ester (KE) would improve resting and exercise hemodynamics …
BACKGROUND: Heart failure triggers a shift in myocardial metabolic substrate utilization, favoring the ketone body 3-hydroxybutyrate …
614 results