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Reconstructed Serine 288 in the Left Flipper Region of the Rat P2X7 Receptor Stabilizes Nonsensitized States.
Ishchenko Y, Novosolova N, Khafizov K, Bart G, Timonina A, Fayuk D, Skorinkin A, Giniatullin R. Ishchenko Y, et al. Biochemistry. 2017 Jul 5;56(26):3394-3402. doi: 10.1021/acs.biochem.7b00258. Epub 2017 Jun 26. Biochemistry. 2017. PMID: 28616989
GoLoco motif proteins binding to Galpha(i1): insights from molecular simulations.
Khafizov K. Khafizov K. J Mol Model. 2009 Dec;15(12):1491-9. doi: 10.1007/s00894-009-0516-z. Epub 2009 May 14. J Mol Model. 2009. PMID: 19437048 Free PMC article.
AlignMe--a membrane protein sequence alignment web server.
Stamm M, Staritzbichler R, Khafizov K, Forrest LR. Stamm M, et al. Nucleic Acids Res. 2014 Jul;42(Web Server issue):W246-51. doi: 10.1093/nar/gku291. Epub 2014 Apr 21. Nucleic Acids Res. 2014. PMID: 24753425 Free PMC article.
Alignment of helical membrane protein sequences using AlignMe.
Stamm M, Staritzbichler R, Khafizov K, Forrest LR. Stamm M, et al. PLoS One. 2013;8(3):e57731. doi: 10.1371/journal.pone.0057731. Epub 2013 Mar 4. PLoS One. 2013. PMID: 23469223 Free PMC article.
Investigation of the sodium-binding sites in the sodium-coupled betaine transporter BetP.
Khafizov K, Perez C, Koshy C, Quick M, Fendler K, Ziegler C, Forrest LR. Khafizov K, et al. Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):E3035-44. doi: 10.1073/pnas.1209039109. Epub 2012 Oct 9. Proc Natl Acad Sci U S A. 2012. PMID: 23047697 Free PMC article.
Mutating the residues proposed to form the two binding sites increased the apparent K(m) and K(d) for sodium, as measured by betaine uptake, tryptophan fluorescence, and (22)Na(+) binding, and also diminished the transient currents measured in proteoliposomes using …
Mutating the residues proposed to form the two binding sites increased the apparent K(m) and K(d) for sodium, as measured by b …
The role of trimerization in the osmoregulated betaine transporter BetP.
Perez C, Khafizov K, Forrest LR, Krämer R, Ziegler C. Perez C, et al. EMBO Rep. 2011 Jun 17;12(8):804-10. doi: 10.1038/embor.2011.102. EMBO Rep. 2011. PMID: 21681199 Free PMC article.
Structural asymmetry in a trimeric Na+/betaine symporter, BetP, from Corynebacterium glutamicum.
Tsai CJ, Khafizov K, Hakulinen J, Forrest LR, Forrest LR, Krämer R, Kühlbrandt W, Ziegler C. Tsai CJ, et al. J Mol Biol. 2011 Apr 1;407(3):368-81. doi: 10.1016/j.jmb.2011.01.028. Epub 2011 Jan 31. J Mol Biol. 2011. PMID: 21281647
Trends in structural coverage of the protein universe and the impact of the Protein Structure Initiative.
Khafizov K, Madrid-Aliste C, Almo SC, Fiser A. Khafizov K, et al. Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3733-8. doi: 10.1073/pnas.1321614111. Epub 2014 Feb 24. Proc Natl Acad Sci U S A. 2014. PMID: 24567391 Free PMC article.
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