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Forging a link between oncogenic signaling and immunosuppression in melanoma.

Khalili JS, Hwu P, Lizée G. Khalili JS, et al. Oncoimmunology. 2013 Feb 1;2(2):e22745. doi: 10.4161/onci.22745. Oncoimmunology. 2013. PMID: 23525189 Free PMC article.

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Lovastatin inhibits T-cell proliferation while preserving the cytolytic function of EBV, CMV, and MART-1-specific CTLs.

Li D, Li Y, Hernandez JA, Patenia R, Kim TK, Khalili J, Dougherty MC, Hanley PJ, Bollard CM, Komanduri KV, Hwu P, Champlin RE, Radvanyi LG, Molldrem JJ, Ma Q. Li D, et al. J Immunother. 2010 Nov-Dec;33(9):975-82. doi: 10.1097/CJI.0b013e3181fb0486. J Immunother. 2010. PMID: 20948439 Free PMC article.

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Natural splice variant of MHC class I cytoplasmic tail enhances dendritic cell-induced CD8+ T-cell responses and boosts anti-tumor immunity.

Rodríguez-Cruz TG, Liu S, Khalili JS, Whittington M, Zhang M, Overwijk W, Lizée G. Rodríguez-Cruz TG, et al. Among authors: khalili js. PLoS One. 2011;6(8):e22939. doi: 10.1371/journal.pone.0022939. Epub 2011 Aug 10. PLoS One. 2011. PMID: 21860662 Free PMC article.

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Combination small molecule MEK and PI3K inhibition enhances uveal melanoma cell death in a mutant GNAQ- and GNA11-dependent manner.

Khalili JS, Yu X, Wang J, Hayes BC, Davies MA, Lizee G, Esmaeli B, Woodman SE. Khalili JS, et al. Clin Cancer Res. 2012 Aug 15;18(16):4345-55. doi: 10.1158/1078-0432.CCR-11-3227. Epub 2012 Jun 25. Clin Cancer Res. 2012. PMID: 22733540 Free PMC article.

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Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma.

Khalili JS, Liu S, Rodríguez-Cruz TG, Whittington M, Wardell S, Liu C, Zhang M, Cooper ZA, Frederick DT, Li Y, Zhang M, Joseph RW, Bernatchez C, Ekmekcioglu S, Grimm E, Radvanyi LG, Davis RE, Davies MA, Wargo JA, Hwu P, Lizée G. Khalili JS, et al. Clin Cancer Res. 2012 Oct 1;18(19):5329-40. doi: 10.1158/1078-0432.CCR-12-1632. Epub 2012 Jul 31. Clin Cancer Res. 2012. PMID: 22850568 Free PMC article.

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In silico prediction of tumor antigens derived from functional missense mutations of the cancer gene census.

Khalili JS, Hanson RW, Szallasi Z. Khalili JS, et al. Oncoimmunology. 2012 Nov 1;1(8):1281-1289. doi: 10.4161/onci.21511. Oncoimmunology. 2012. PMID: 23243591 Free PMC article.

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B-Raf regulation of integrin α4β1-mediated resistance to shear stress through changes in cell spreading and cytoskeletal association in T cells.

Brown WS, Khalili JS, Rodriguez-Cruz TG, Lizee G, McIntyre BW. Brown WS, et al. Among authors: khalili js. J Biol Chem. 2014 Aug 15;289(33):23141-23153. doi: 10.1074/jbc.M114.562918. Epub 2014 Jun 16. J Biol Chem. 2014. PMID: 24936068 Free PMC article.

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BRAFV600E Co-opts a Conserved MHC Class I Internalization Pathway to Diminish Antigen Presentation and CD8+ T-cell Recognition of Melanoma.

Bradley SD, Chen Z, Melendez B, Talukder A, Khalili JS, Rodriguez-Cruz T, Liu S, Whittington M, Deng W, Li F, Bernatchez C, Radvanyi LG, Davies MA, Hwu P, Lizée G. Bradley SD, et al. Among authors: khalili js. Cancer Immunol Res. 2015 Jun;3(6):602-9. doi: 10.1158/2326-6066.CIR-15-0030. Epub 2015 Mar 20. Cancer Immunol Res. 2015. PMID: 25795007 Free PMC article.

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SLC45A2: A Melanoma Antigen with High Tumor Selectivity and Reduced Potential for Autoimmune Toxicity.

Park J, Talukder AH, Lim SA, Kim K, Pan K, Melendez B, Bradley SD, Jackson KR, Khalili JS, Wang J, Creasy C, Pan BF, Woodman SE, Bernatchez C, Hawke D, Hwu P, Lee KM, Roszik J, Lizée G, Yee C. Park J, et al. Among authors: khalili js. Cancer Immunol Res. 2017 Aug;5(8):618-629. doi: 10.1158/2326-6066.CIR-17-0051. Epub 2017 Jun 19. Cancer Immunol Res. 2017. PMID: 28630054 Free PMC article.

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Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity.

Punt S, Malu S, McKenzie JA, Manrique SZ, Doorduijn EM, Mbofung RM, Williams L, Silverman DA, Ashkin EL, Dominguez AL, Wang Z, Chen JQ, Maiti SN, Tieu TN, Liu C, Xu C, Forget MA, Haymaker C, Khalili JS, Satani N, Muller F, Cooper LJN, Overwijk WW, Amaria RN, Bernatchez C, Heffernan TP, Peng W, Roszik J, Hwu P. Punt S, et al. Among authors: khalili js. Cancer Immunol Immunother. 2021 Apr;70(4):1101-1113. doi: 10.1007/s00262-020-02748-9. Epub 2020 Oct 29. Cancer Immunol Immunother. 2021. PMID: 33123754 Free PMC article.

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