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Design, synthesis and screening of indole acetic acid-based tri-azo moieties as antioxidants, anti-microbial and cytotoxic agents.
Javaid M, Haq IU, Nadeem H, Fatima H, Khan AU, Irshad N. Javaid M, et al. Among authors: khan au. Front Pharmacol. 2023 Feb 27;14:1084181. doi: 10.3389/fphar.2023.1084181. eCollection 2023. Front Pharmacol. 2023. PMID: 36923352 Free PMC article.
These synthetic molecules possess good cytotoxic potential in the Brine Shrimp Lethality screening; 5c, 5d, and 5f exhibited LC(50 =)5.7 mug/mL. In the protein kinase inhibition assay, 5a, 5b, and 5g demonstrated inhibitory potential, showcasing the zone of inhibition as 7 …
These synthetic molecules possess good cytotoxic potential in the Brine Shrimp Lethality screening; 5c, 5d, and 5f exhibited LC(50 =) …
Synthesis, characterization, and in vitro antimicrobial activities of 5-alkenyl/hydroxyalkenyl-2-phenylamine-1,3,4-oxadiazoles and thiadiazoles.
Farshori NN, Banday MR, Ahmad A, Khan AU, Rauf A. Farshori NN, et al. Among authors: khan au. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1933-8. doi: 10.1016/j.bmcl.2010.01.126. Epub 2010 Feb 1. Bioorg Med Chem Lett. 2010. PMID: 20172722
The investigation of antimicrobial screening revealed that compounds 3c, 3d, 5c, 5d and compounds 3b, 5b, showed good antibacterial and antifungal activities, respectively....
The investigation of antimicrobial screening revealed that compounds 3c, 3d, 5c, 5d and compounds 3b, 5b, showed good antibacterial a …