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DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesis.
Starokadomskyy P, Gemelli T, Rios JJ, Xing C, Wang RC, Li H, Pokatayev V, Dozmorov I, Khan S, Miyata N, Fraile G, Raj P, Xu Z, Xu Z, Ma L, Lin Z, Wang H, Yang Y, Ben-Amitai D, Orenstein N, Mussaffi H, Baselga E, Tadini G, Grunebaum E, Sarajlija A, Krzewski K, Wakeland EK, Yan N, de la Morena MT, Zinn AR, Burstein E. Starokadomskyy P, et al. Among authors: khan s. Nat Immunol. 2016 May;17(5):495-504. doi: 10.1038/ni.3409. Epub 2016 Mar 28. Nat Immunol. 2016. PMID: 27019227 Free PMC article.
Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.
Raj P, Rai E, Song R, Khan S, Wakeland BE, Viswanathan K, Arana C, Liang C, Zhang B, Dozmorov I, Carr-Johnson F, Mitrovic M, Wiley GB, Kelly JA, Lauwerys BR, Olsen NJ, Cotsapas C, Garcia CK, Wise CA, Harley JB, Nath SK, James JA, Jacob CO, Tsao BP, Pasare C, Karp DR, Li QZ, Gaffney PM, Wakeland EK. Raj P, et al. Among authors: khan s. Elife. 2016 Feb 15;5:e12089. doi: 10.7554/eLife.12089. Elife. 2016. PMID: 26880555 Free PMC article.
RNA sequencing reveals the consequences of a novel insertion in dedicator of cytokinesis-8.
Khan S, Kuruvilla M, Hagin D, Wakeland B, Liang C, Vishwanathan K, Gatti RA, Torgersen TR, Abraham RS, Wakeland EK, van Oers NSC, de la Morena MT. Khan S, et al. J Allergy Clin Immunol. 2016 Jul;138(1):289-292.e6. doi: 10.1016/j.jaci.2015.11.033. Epub 2016 Feb 13. J Allergy Clin Immunol. 2016. PMID: 26883462 No abstract available.
FOXN1 compound heterozygous mutations cause selective thymic hypoplasia in humans.
Du Q, Huynh LK, Coskun F, Molina E, King MA, Raj P, Khan S, Dozmorov I, Seroogy CM, Wysocki CA, Padron GT, Yates TR, Markert ML, de la Morena MT, van Oers NS. Du Q, et al. Among authors: khan s. J Clin Invest. 2019 Nov 1;129(11):4724-4738. doi: 10.1172/JCI127565. J Clin Invest. 2019. PMID: 31566583 Free PMC article.
Association between Antibiotic Exposure and Systemic Immune Parameters in Cancer Patients Receiving Checkpoint Inhibitor Therapy.
von Itzstein MS, Gonugunta AS, Sheffield T, Homsi J, Dowell JE, Koh AY, Raj P, Fattah F, Wang Y, Basava VS, Khan S, Park JY, Popat V, Saltarski JM, Gloria-McCutchen Y, Hsiehchen D, Ostmeyer J, Xie Y, Li QZ, Wakeland EK, Gerber DE. von Itzstein MS, et al. Among authors: khan s. Cancers (Basel). 2022 Mar 4;14(5):1327. doi: 10.3390/cancers14051327. Cancers (Basel). 2022. PMID: 35267634 Free PMC article.
T-cell tolerant fraction as a predictor of immune-related adverse events.
Ostmeyer J, Park JY, von Itzstein MS, Hsiehchen D, Fattah F, Gwin M, Catalan R, Khan S, Raj P, Wakeland EK, Xie Y, Gerber DE. Ostmeyer J, et al. Among authors: khan s. J Immunother Cancer. 2023 Aug;11(8):e006437. doi: 10.1136/jitc-2022-006437. J Immunother Cancer. 2023. PMID: 37580069 Free PMC article.
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