Kharitonenkov A - Search Results

1

The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21.

Kharitonenkov A, Wroblewski VJ, Koester A, Chen YF, Clutinger CK, Tigno XT, Hansen BC, Shanafelt AB, Etgen GJ. Kharitonenkov A, et al. Endocrinology. 2007 Feb;148(2):774-81. doi: 10.1210/en.2006-1168. Epub 2006 Oct 26. Endocrinology. 2007. PMID: 17068132

2

FGF-21 as a novel metabolic regulator.

Kharitonenkov A, Shiyanova TL, Koester A, Ford AM, Micanovic R, Galbreath EJ, Sandusky GE, Hammond LJ, Moyers JS, Owens RA, Gromada J, Brozinick JT, Hawkins ED, Wroblewski VJ, Li DS, Mehrbod F, Jaskunas SR, Shanafelt AB. Kharitonenkov A, et al. J Clin Invest. 2005 Jun;115(6):1627-35. doi: 10.1172/JCI23606. Epub 2005 May 2. J Clin Invest. 2005. PMID: 15902306 Free PMC article.

3

Fibroblast growth factor-21 as a therapeutic agent for metabolic diseases.

Kharitonenkov A, Shanafelt AB. Kharitonenkov A, et al. BioDrugs. 2008;22(1):37-44. doi: 10.2165/00063030-200822010-00004. BioDrugs. 2008. PMID: 18215089 Review.

4

FGF21: a novel prospect for the treatment of metabolic diseases.

Kharitonenkov A, Shanafelt AB. Kharitonenkov A, et al. Curr Opin Investig Drugs. 2009 Apr;10(4):359-64. Curr Opin Investig Drugs. 2009. PMID: 19337957 Review.

5

LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys.

Adams AC, Halstead CA, Hansen BC, Irizarry AR, Martin JA, Myers SR, Reynolds VL, Smith HW, Wroblewski VJ, Kharitonenkov A. Adams AC, et al. Among authors: kharitonenkov a. PLoS One. 2013 Jun 18;8(6):e65763. doi: 10.1371/journal.pone.0065763. Print 2013. PLoS One. 2013. PMID: 23823755 Free PMC article.

6

FGF-21/FGF-21 receptor interaction and activation is determined by betaKlotho.

Kharitonenkov A, Dunbar JD, Bina HA, Bright S, Moyers JS, Zhang C, Ding L, Micanovic R, Mehrbod SF, Knierman MD, Hale JE, Coskun T, Shanafelt AB. Kharitonenkov A, et al. J Cell Physiol. 2008 Apr;215(1):1-7. doi: 10.1002/jcp.21357. J Cell Physiol. 2008. PMID: 18064602

7

Fibroblast growth factor 21 corrects obesity in mice.

Coskun T, Bina HA, Schneider MA, Dunbar JD, Hu CC, Chen Y, Moller DE, Kharitonenkov A. Coskun T, et al. Among authors: kharitonenkov a. Endocrinology. 2008 Dec;149(12):6018-27. doi: 10.1210/en.2008-0816. Epub 2008 Aug 7. Endocrinology. 2008. PMID: 18687777

8

Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity.

Berglund ED, Li CY, Bina HA, Lynes SE, Michael MD, Shanafelt AB, Kharitonenkov A, Wasserman DH. Berglund ED, et al. Among authors: kharitonenkov a. Endocrinology. 2009 Sep;150(9):4084-93. doi: 10.1210/en.2009-0221. Epub 2009 May 21. Endocrinology. 2009. PMID: 19470704 Free PMC article.

9

Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis.

Badman MK, Koester A, Flier JS, Kharitonenkov A, Maratos-Flier E. Badman MK, et al. Among authors: kharitonenkov a. Endocrinology. 2009 Nov;150(11):4931-40. doi: 10.1210/en.2009-0532. Epub 2009 Oct 9. Endocrinology. 2009. PMID: 19819944 Free PMC article.

10

Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319.

Kharitonenkov A, Beals JM, Micanovic R, Strifler BA, Rathnachalam R, Wroblewski VJ, Li S, Koester A, Ford AM, Coskun T, Dunbar JD, Cheng CC, Frye CC, Bumol TF, Moller DE. Kharitonenkov A, et al. PLoS One. 2013;8(3):e58575. doi: 10.1371/journal.pone.0058575. Epub 2013 Mar 11. PLoS One. 2013. PMID: 23536797 Free PMC article.

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