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87 results
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FGF21 as a therapeutic reagent.
Zhao Y, Dunbar JD, Kharitonenkov A. Zhao Y, et al. Among authors: kharitonenkov a. Adv Exp Med Biol. 2012;728:214-28. doi: 10.1007/978-1-4614-0887-1_14. Adv Exp Med Biol. 2012. PMID: 22396172 Review.
FGF21: The center of a transcriptional nexus in metabolic regulation.
Adams AC, Kharitonenkov A. Adams AC, et al. Among authors: kharitonenkov a. Curr Diabetes Rev. 2012 Jul 1;8(4):285-93. doi: 10.2174/157339912800840505. Curr Diabetes Rev. 2012. PMID: 22587513 Review.
Physiology and Endocrinology Symposium: FGF21: Insights into mechanism of action from preclinical studies.
Antonellis PJ, Kharitonenkov A, Adams AC. Antonellis PJ, et al. Among authors: kharitonenkov a. J Anim Sci. 2014 Feb;92(2):407-13. doi: 10.2527/jas.2013-7076. Epub 2014 Jan 7. J Anim Sci. 2014. PMID: 24398833
Obesity is a fibroblast growth factor 21 (FGF21)-resistant state.
Fisher FM, Chui PC, Antonellis PJ, Bina HA, Kharitonenkov A, Flier JS, Maratos-Flier E. Fisher FM, et al. Among authors: kharitonenkov a. Diabetes. 2010 Nov;59(11):2781-9. doi: 10.2337/db10-0193. Epub 2010 Aug 3. Diabetes. 2010. PMID: 20682689 Free PMC article.
Fibroblast growth factor 21 is not required for the reductions in circulating insulin-like growth factor-1 or global cell proliferation rates in response to moderate calorie restriction in adult mice.
Thompson AC, Bruss MD, Nag N, Kharitonenkov A, Adams AC, Hellerstein MK. Thompson AC, et al. Among authors: kharitonenkov a. PLoS One. 2014 Nov 4;9(11):e111418. doi: 10.1371/journal.pone.0111418. eCollection 2014. PLoS One. 2014. PMID: 25369265 Free PMC article.
Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity.
Agrawal A, Parlee S, Perez-Tilve D, Li P, Pan J, Mroz PA, Kruse Hansen AM, Andersen B, Finan B, Kharitonenkov A, DiMarchi RD. Agrawal A, et al. Among authors: kharitonenkov a. Mol Metab. 2018 Jul;13:45-55. doi: 10.1016/j.molmet.2018.05.003. Epub 2018 May 11. Mol Metab. 2018. PMID: 29789271 Free PMC article.
Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21.
Li Y, Wong K, Giles A, Jiang J, Lee JW, Adams AC, Kharitonenkov A, Yang Q, Gao B, Guarente L, Zang M. Li Y, et al. Among authors: kharitonenkov a. Gastroenterology. 2014 Feb;146(2):539-49.e7. doi: 10.1053/j.gastro.2013.10.059. Epub 2013 Nov 1. Gastroenterology. 2014. PMID: 24184811 Free PMC article.
Inventing new medicines: The FGF21 story.
Kharitonenkov A, Adams AC. Kharitonenkov A, et al. Mol Metab. 2013 Dec 27;3(3):221-9. doi: 10.1016/j.molmet.2013.12.003. eCollection 2014 Jun. Mol Metab. 2013. PMID: 24749049 Free PMC article. Review.
Photoperiodic regulation of FGF21 production in the Siberian hamster.
Samms RJ, Fowler MJ, Cooper S, Emmerson P, Coskun T, Adams AC, Kharitonenkov A, Tsintzas K, Ebling FJ. Samms RJ, et al. Among authors: kharitonenkov a. Horm Behav. 2014 Jun;66(1):180-5. doi: 10.1016/j.yhbeh.2014.03.013. Horm Behav. 2014. PMID: 24909854
Overexpression of β-Klotho in Adipose Tissue Sensitizes Male Mice to Endogenous FGF21 and Provides Protection From Diet-Induced Obesity.
Samms RJ, Cheng CC, Kharitonenkov A, Gimeno RE, Adams AC. Samms RJ, et al. Among authors: kharitonenkov a. Endocrinology. 2016 Apr;157(4):1467-80. doi: 10.1210/en.2015-1722. Epub 2016 Feb 22. Endocrinology. 2016. PMID: 26901091
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