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An essential role for Scurfin in CD4+CD25+ T regulatory cells.
Khattri R, Cox T, Yasayko SA, Ramsdell F. Khattri R, et al. Nat Immunol. 2003 Apr;4(4):337-42. doi: 10.1038/ni909. Epub 2003 Mar 3. Nat Immunol. 2003. PMID: 12612581
Here we show that Foxp3 is highly expressed by T(R) cells and is associated with T(R) cell activity and phenotype. Scurfin-deficient mice lack T(R) cells, whereas mice that overexpress Foxp3 possess more T(R) cells. ...The forced expression of Foxp3 al …
Here we show that Foxp3 is highly expressed by T(R) cells and is associated with T(R) cell activity and phenotype. Scurfin-def …
The amount of scurfin protein determines peripheral T cell number and responsiveness.
Khattri R, Kasprowicz D, Cox T, Mortrud M, Appleby MW, Brunkow ME, Ziegler SF, Ramsdell F. Khattri R, et al. J Immunol. 2001 Dec 1;167(11):6312-20. doi: 10.4049/jimmunol.167.11.6312. J Immunol. 2001. PMID: 11714795
HIV-1 gp120-specific antibody-dependent cell-mediated cytotoxicity correlates with rate of disease progression.
Baum LL, Cassutt KJ, Knigge K, Khattri R, Margolick J, Rinaldo C, Kleeberger CA, Nishanian P, Henrard DR, Phair J. Baum LL, et al. J Immunol. 1996 Sep 1;157(5):2168-73. J Immunol. 1996. PMID: 8757343 Clinical Trial.
Molecular basis of T cell inactivation by CTLA-4.
Lee KM, Chuang E, Griffin M, Khattri R, Hong DK, Zhang W, Straus D, Samelson LE, Thompson CB, Bluestone JA. Lee KM, et al. Science. 1998 Dec 18;282(5397):2263-6. doi: 10.1126/science.282.5397.2263. Science. 1998. PMID: 9856951
TCR gamma delta cells: a specialized T-cell subset in the immune system.
Bluestone JA, Khattri R, Sciammas R, Sperling AI. Bluestone JA, et al. Annu Rev Cell Dev Biol. 1995;11:307-53. doi: 10.1146/annurev.cb.11.110195.001515. Annu Rev Cell Dev Biol. 1995. PMID: 8689560 Review.
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