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The impact of CD4+CD25+ Treg on tumor specific CD8+ T cell cytotoxicity and cancer.
Khazaie K, von Boehmer H. Khazaie K, et al. Semin Cancer Biol. 2006 Apr;16(2):124-36. doi: 10.1016/j.semcancer.2005.11.006. Epub 2006 Jan 26. Semin Cancer Biol. 2006. PMID: 16443370 Review.
Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma.
Bonertz A, Weitz J, Pietsch DH, Rahbari NN, Schlude C, Ge Y, Juenger S, Vlodavsky I, Khazaie K, Jaeger D, Reissfelder C, Antolovic D, Aigner M, Koch M, Beckhove P. Bonertz A, et al. Among authors: khazaie k. J Clin Invest. 2009 Nov;119(11):3311-21. doi: 10.1172/JCI39608. Epub 2009 Oct 5. J Clin Invest. 2009. PMID: 19809157 Free PMC article.
T-regulatory cells shift from a protective anti-inflammatory to a cancer-promoting proinflammatory phenotype in polyposis.
Gounaris E, Blatner NR, Dennis K, Magnusson F, Gurish MF, Strom TB, Beckhove P, Gounari F, Khazaie K. Gounaris E, et al. Among authors: khazaie k. Cancer Res. 2009 Jul 1;69(13):5490-7. doi: 10.1158/0008-5472.CAN-09-0304. Cancer Res. 2009. PMID: 19570783 Free PMC article.
Current developments with peptide-based human tumor vaccines.
Khazaie K, Bonertz A, Beckhove P. Khazaie K, et al. Curr Opin Oncol. 2009 Nov;21(6):524-30. doi: 10.1097/CCO.0b013e328331a78e. Curr Opin Oncol. 2009. PMID: 19770763 Review.
T-cell Expression of IL10 Is Essential for Tumor Immune Surveillance in the Small Intestine.
Dennis KL, Saadalla A, Blatner NR, Wang S, Venkateswaran V, Gounari F, Cheroutre H, Weaver CT, Roers A, Egilmez NK, Khazaie K. Dennis KL, et al. Among authors: khazaie k. Cancer Immunol Res. 2015 Jul;3(7):806-14. doi: 10.1158/2326-6066.CIR-14-0169. Epub 2015 Apr 8. Cancer Immunol Res. 2015. PMID: 25855122 Free PMC article.
Adenomatous polyps are driven by microbe-instigated focal inflammation and are controlled by IL-10-producing T cells.
Dennis KL, Wang Y, Blatner NR, Wang S, Saadalla A, Trudeau E, Roers A, Weaver CT, Lee JJ, Gilbert JA, Chang EB, Khazaie K. Dennis KL, et al. Among authors: khazaie k. Cancer Res. 2013 Oct 1;73(19):5905-13. doi: 10.1158/0008-5472.CAN-13-1511. Epub 2013 Aug 16. Cancer Res. 2013. PMID: 23955389 Free PMC article.
The significant role of mast cells in cancer.
Khazaie K, Blatner NR, Khan MW, Gounari F, Gounaris E, Dennis K, Bonertz A, Tsai FN, Strouch MJ, Cheon E, Phillips JD, Beckhove P, Bentrem DJ. Khazaie K, et al. Cancer Metastasis Rev. 2011 Mar;30(1):45-60. doi: 10.1007/s10555-011-9286-z. Cancer Metastasis Rev. 2011. PMID: 21287360 Review.
Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity.
Magnusson FC, Liblau RS, von Boehmer H, Pittet MJ, Lee JW, Turley SJ, Khazaie K. Magnusson FC, et al. Among authors: khazaie k. Gastroenterology. 2008 Apr;134(4):1028-37. doi: 10.1053/j.gastro.2008.01.070. Epub 2008 Jan 30. Gastroenterology. 2008. PMID: 18395084
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo.
Chen ML, Pittet MJ, Gorelik L, Flavell RA, Weissleder R, von Boehmer H, Khazaie K. Chen ML, et al. Among authors: khazaie k. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):419-24. doi: 10.1073/pnas.0408197102. Epub 2004 Dec 27. Proc Natl Acad Sci U S A. 2005. PMID: 15623559 Free PMC article.
In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro.
Klein L, Khazaie K, von Boehmer H. Klein L, et al. Among authors: khazaie k. Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8886-91. doi: 10.1073/pnas.1533365100. Epub 2003 Jul 11. Proc Natl Acad Sci U S A. 2003. PMID: 12857946 Free PMC article.
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