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Promoter engineering-mediated Tuning of esterase and transaminase expression for the chemoenzymatic synthesis of sitagliptin phosphate at the kilogram-scale.
Khobragade TP, Yu S, Jung H, Patil MD, Sarak S, Pagar AD, Jeon H, Lee S, Giri P, Kim GH, Cho SS, Park SH, Park HJ, Kang HM, Lee SR, Lee MS, Kim JH, Choi IS, Yun H. Khobragade TP, et al. Biotechnol Bioeng. 2021 Aug;118(8):3263-3268. doi: 10.1002/bit.27819. Epub 2021 May 21. Biotechnol Bioeng. 2021. PMID: 33990942