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Year Number of Results
2013 1
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2020 7
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Page 1
ZC3H4, a novel regulator of mitochondrial complex I, impacts prostate stromal cell senescence, attachment, adhesion and anoikis resistance.
Liu TT, Carrarini MJ, Myklebust LK, Skalitzky KO, El-Khoury N, Sipula IJ, Chang A, Soman V, Liu A, Ihejirika N, Chandran UR, Jurczak MJ, Ricke WA, DeFranco DB, Pascal LE. Liu TT, et al. Among authors: el khoury n. Cell Death Dis. 2025 Oct 21;16(1):741. doi: 10.1038/s41419-025-08027-8. Cell Death Dis. 2025. PMID: 41120279 Free PMC article.
Transferrin receptor-mediated transport at the blood-brain barrier is elevated during early development and maintained across aging and in an Alzheimer's mouse model.
Torres VO, Pizzo ME, Chan D, Dugas JC, Huynh D, Joy D, Liang EK, Sarrafha L, Becerra I, Chau R, Chew KS, Chow J, Discenza CB, Earr TK, Furaso L, Khoury N, Lechtenberg KJ, Leung AW, Nguyen HN, Ojo ES, Roche E, Simon MJ, Solanoy H, Tong M, Tong RK, Henne K, Lewcock JW, Watts RJ, Calvert ME, Thorne RG, Zuchero YJY. Torres VO, et al. Among authors: khoury n. J Cereb Blood Flow Metab. 2025 Aug 16:271678X251361997. doi: 10.1177/0271678X251361997. Online ahead of print. J Cereb Blood Flow Metab. 2025. PMID: 40817783 Free PMC article.
Transferrin receptor-targeted anti-amyloid antibody enhances brain delivery and mitigates ARIA.
Pizzo ME, Plowey ED, Khoury N, Kwan W, Abettan J, DeVos SL, Discenza CB, Earr T, Joy D, Lye-Barthel M, Roche E, Chan D, Dugas JC, Gadkar K, Hamann S, Meisner R, Sebalusky J, Silva Amaral AC, Becerra I, Chau R, Chow J, Clemens AJ, Dennis MS, Duque J, Fusaro L, Getz JA, Kariolis MS, Kim DJ, Lechtenberg KJ, Leung AW, Moshkforoush A, Nguyen HN, Ojo ES, Thomsen ER, Torres VO, Sanchez PE, Shan L, Silverman AP, Sweeney ZK, Solanoy H, Tong R, Calvert ME, Watts RJ, Thorne RG, Weinreb PH, Walsh DM, Lewcock JW, Bussiere T, Zuchero YJY. Pizzo ME, et al. Among authors: khoury n. Science. 2025 Aug 7;389(6760):eads3204. doi: 10.1126/science.ads3204. Epub 2025 Aug 7. Science. 2025. PMID: 40773560
Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution.
Khoury N, Pizzo ME, Discenza CB, Joy D, Tatarakis D, Todorov MI, Negwer M, Ha C, De Melo GL, Sarrafha L, Simon MJ, Chan D, Chau R, Chew KS, Chow J, Clemens A, Robles-Colmenares Y, Dugas JC, Duque J, Kaltenecker D, Kane H, Leung A, Lozano E, Moshkforoush A, Roche E, Sandmann T, Tong M, Xa K, Zhou Y, Lewcock JW, Ertürk A, Thorne RG, Calvert MEK, Yu Zuchero YJ. Khoury N, et al. Nat Commun. 2025 Feb 20;16(1):1822. doi: 10.1038/s41467-025-57108-x. Nat Commun. 2025. PMID: 39979268 Free PMC article.
Physiologic and structural characterization of desisobutyryl-ciclesonide, a selective glucocorticoid receptor modulator in newborn rats.
Jaumotte JD, El Khoury N, Min CK, Wang J, Madigan C, Jano A, Russo Kobylski RJ, Solt LA, Dhavan RS, Short KL, Lei T, Chandran U, Cole TJ, Monaghan-Nichols AP, Sampath V, Houtman R, Nettles KW, DeFranco DB. Jaumotte JD, et al. Among authors: el khoury n. PNAS Nexus. 2024 Dec 26;4(1):pgae573. doi: 10.1093/pnasnexus/pgae573. eCollection 2025 Jan. PNAS Nexus. 2024. PMID: 39781096 Free PMC article.
Benign prostatic hyperplasia nodules in patients treated with celecoxib and/or finasteride have reduced levels of NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, a mitochondrial protein essential for efficient function of the electron transport chain.
Liu TT, Igarashi T, El-Khoury N, Ihejirika N, Paxton K, Jaumotte J, Dhir R, Hudson CN, Nelson JB, DeFranco DB, Yoshimura N, Wang Z, Pascal LE. Liu TT, et al. Among authors: el khoury n. Prostate. 2024 Oct;84(14):1309-1319. doi: 10.1002/pros.24766. Epub 2024 Jul 14. Prostate. 2024. PMID: 39004950 Free PMC article.
40 results