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A phase 1 Bayesian dose selection study of bortezomib and sunitinib in patients with refractory solid tumor malignancies.
Harvey RD, Owonikoko TK, Lewis CM, Akintayo A, Chen Z, Tighiouart M, Ramalingam SS, Fanucchi MP, Nadella P, Rogatko A, Shin DM, El-Rayes B, Khuri FR, Kauh JS. Harvey RD, et al. Among authors: Khuri FR. Br J Cancer. 2013 Mar 5;108(4):762-5. doi: 10.1038/bjc.2012.604. Epub 2013 Jan 15. Br J Cancer. 2013. PMID: 23322195 Free PMC article. Clinical Trial.
Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin.
Elf S, Lin R, Xia S, Pan Y, Shan C, Wu S, Lonial S, Gaddh M, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Boggon TJ, Fan J, Chen J. Elf S, et al. Among authors: Khuri FR. Oncogene. 2017 Jan 12;36(2):254-262. doi: 10.1038/onc.2016.196. Epub 2016 Jun 6. Oncogene. 2017. PMID: 27270429 Free PMC article.
OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc.
Ivanov AA, Gonzalez-Pecchi V, Khuri LF, Niu Q, Wang Y, Xu Y, Bai Y, Mo X, Prochownik EV, Johns MA, Du Y, Khuri FR, Fu H. Ivanov AA, et al. Among authors: Khuri LF, Khuri FR. Oncogene. 2017 Oct 19;36(42):5852-5860. doi: 10.1038/onc.2017.180. Epub 2017 Jun 19. Oncogene. 2017. PMID: 28628118 Free PMC article.
RSK2 signals through stathmin to promote microtubule dynamics and tumor metastasis.
Alesi GN, Jin L, Li D, Magliocca KR, Kang Y, Chen ZG, Shin DM, Khuri FR, Kang S. Alesi GN, et al. Among authors: Khuri FR. Oncogene. 2016 Oct 13;35(41):5412-5421. doi: 10.1038/onc.2016.79. Epub 2016 Apr 4. Oncogene. 2016. PMID: 27041561 Free PMC article.
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