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Cannabidiol.
[No authors listed] [No authors listed] 2023 Feb 16. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2023 Feb 16. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31644197 Free Books & Documents. Review.
High daily doses of cannabidiol are associated with frequent serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent liver injury with jaundice. The lower doses of cannabidiol found typically in over-the-counter CBD products a …
High daily doses of cannabidiol are associated with frequent serum enzyme elevations during therapy, but has not been linked to cases …
Beyond THC and Endocannabinoids.
Pacher P, Kogan NM, Mechoulam R. Pacher P, et al. Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:637-659. doi: 10.1146/annurev-pharmtox-010818-021441. Epub 2019 Oct 3. Annu Rev Pharmacol Toxicol. 2020. PMID: 31580774 Review.
Numerous endocannabinoid-like compounds have been discovered. The Cannabis plant constituent cannabidiol (CBD) was found to exert beneficial effects in many preclinical disease models ranging from epilepsy, cardiovascular disease, inflammation, and autoimmuni …
Numerous endocannabinoid-like compounds have been discovered. The Cannabis plant constituent cannabidiol (CBD) was found to exert ben …
The nephrologist's guide to cannabis and cannabinoids.
Rein JL. Rein JL. Curr Opin Nephrol Hypertens. 2020 Mar;29(2):248-257. doi: 10.1097/MNH.0000000000000590. Curr Opin Nephrol Hypertens. 2020. PMID: 31972598 Free PMC article. Review.
RECENT FINDINGS: Cannabis may have medicinal benefits for treating symptoms of advanced chronic kidney disease (CKD) and end-stage renal disease including as a pain adjuvant potentially reducing the need for opioids. ...SUMMARY: Patients and healthcare profes …
RECENT FINDINGS: Cannabis may have medicinal benefits for treating symptoms of advanced chronic kidney disease (CKD) and end-s …
CBGA ameliorates inflammation and fibrosis in nephropathy.
Suzuki S, Fleig A, Penner R. Suzuki S, et al. Sci Rep. 2023 Apr 18;13(1):6341. doi: 10.1038/s41598-023-33507-2. Sci Rep. 2023. PMID: 37072467 Free PMC article.
The endocannabinoid system has recently emerged to contribute to kidney disease, however, the therapeutic properties of cannabinoids in kidney disease remain largely unknown. In this study, we determined whether CBD and CBGA can attenuate kidney
The endocannabinoid system has recently emerged to contribute to kidney disease, however, the therapeutic properties of cannab …
Adenosine-Related Mechanisms in Non-Adenosine Receptor Drugs.
Jacobson KA, Reitman ML. Jacobson KA, et al. Cells. 2020 Apr 13;9(4):956. doi: 10.3390/cells9040956. Cells. 2020. PMID: 32295065 Free PMC article. Review.
Non-AR mechanisms include raising adenosine levels by inhibiting adenosine transport (e.g., ticagrelor, ethanol, and cannabidiol), affecting intracellular metabolic pathways (e.g., methotrexate, nicotinamide riboside, salicylate, and 5-aminoimidazole-4-carboxamide riboside …
Non-AR mechanisms include raising adenosine levels by inhibiting adenosine transport (e.g., ticagrelor, ethanol, and cannabidiol), af …
Cannabinoids for Symptom Management in Patients with Kidney Failure: A Narrative Review.
Worth H, O'Hara DV, Agarwal N, Collister D, Brennan F, Smyth B. Worth H, et al. Clin J Am Soc Nephrol. 2022 Jun;17(6):911-921. doi: 10.2215/CJN.11560821. Epub 2022 Jan 5. Clin J Am Soc Nephrol. 2022. PMID: 34987023 Free PMC article. Review.
There is growing interest in the potential for cannabinoids, including cannabidiol and tetrahydrocannabinol, to treat symptoms across a wide range of chronic diseases. ...In this review, we summarize the pharmacology and pharmacokinetics of cannabinoids, along with …
There is growing interest in the potential for cannabinoids, including cannabidiol and tetrahydrocannabinol, to treat symptoms across …
Regulation of Innate Lymphoid Cells in Acute Kidney Injury: Crosstalk between Cannabidiol and GILZ.
Baban B, Khodadadi H, Vaibhav K, Marchetti C, Riccardi C, Mozaffari MS. Baban B, et al. J Immunol Res. 2020 Feb 25;2020:6056373. doi: 10.1155/2020/6056373. eCollection 2020. J Immunol Res. 2020. PMID: 32185239 Free PMC article.
Thereafter, kidney cells were prepared for flow cytometry analyses. Sham kidneys treated with either cannabidiol or TAT-GILZ displayed similar frequencies of each subset of ILCs compared to DMSO or TAT, respectively. ...Indeed, cannabidiol treatment increased …
Thereafter, kidney cells were prepared for flow cytometry analyses. Sham kidneys treated with either cannabidiol or TAT-GILZ d …
Cannabidiol negatively modulates adenosine A(2A) receptor functioning in living cells.
Sánchez-Fernández N, Gómez-Acero L, Sarasola LI, Argerich J, Chevigné A, Jacobson KA, Ciruela F, Fernández-Dueñas V, Aso E. Sánchez-Fernández N, et al. Acta Neuropsychiatr. 2023 Aug 22:1-5. doi: 10.1017/neu.2023.30. Online ahead of print. Acta Neuropsychiatr. 2023. PMID: 37605951
OBJECTIVES: Cannabidiol (CBD) is a phytocannabinoid with great potential in clinical applications. ...
OBJECTIVES: Cannabidiol (CBD) is a phytocannabinoid with great potential in clinical applications. ...
Evaluation of the role of the cannabidiol system in an animal model of ischemia/reperfusion kidney injury.
Soares RZ, Vuolo F, Dall'Igna DM, Michels M, Crippa JA, Hallak JE, Zuardi AW, Dal-Pizzol F. Soares RZ, et al. Rev Bras Ter Intensiva. 2015 Oct-Dec;27(4):383-9. doi: 10.5935/0103-507X.20150064. Rev Bras Ter Intensiva. 2015. PMID: 26761477 Free PMC article.
OBJECTIVE: This work aimed to investigate the effects of the administration of cannabidiol in a kidney ischemia/reperfusion animal model. METHODS: Kidney injury was induced by 45 minutes of renal ischemia followed by reperfusion. ...CONCLUSION: The cannabi
OBJECTIVE: This work aimed to investigate the effects of the administration of cannabidiol in a kidney ischemia/reperfusion an …
34 results