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Cannabidiol.
[No authors listed] [No authors listed] 2023 Feb 16. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2023 Feb 16. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31644197 Free Books & Documents. Review.
High daily doses of cannabidiol are associated with frequent serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent liver injury with jaundice. The lower doses of cannabidiol found typically in over-the-counter CBD products a …
High daily doses of cannabidiol are associated with frequent serum enzyme elevations during therapy, but has not been linked to cases …
Beyond THC and Endocannabinoids.
Pacher P, Kogan NM, Mechoulam R. Pacher P, et al. Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:637-659. doi: 10.1146/annurev-pharmtox-010818-021441. Epub 2019 Oct 3. Annu Rev Pharmacol Toxicol. 2020. PMID: 31580774 Review.
Numerous endocannabinoid-like compounds have been discovered. The Cannabis plant constituent cannabidiol (CBD) was found to exert beneficial effects in many preclinical disease models ranging from epilepsy, cardiovascular disease, inflammation, and autoimmuni …
Numerous endocannabinoid-like compounds have been discovered. The Cannabis plant constituent cannabidiol (CBD) was found to exert ben …
Impact of Long-Term Cannabidiol (CBD) Treatment on Mouse Kidney Transcriptome.
Rokicki M, Żurowski J, Sawicki S, Ocłoń E, Szmatoła T, Jasielczuk I, Mizera-Szpilka K, Semik-Gurgul E, Gurgul A. Rokicki M, et al. Genes (Basel). 2024 Dec 21;15(12):1640. doi: 10.3390/genes15121640. Genes (Basel). 2024. PMID: 39766907 Free PMC article.
BACKGROUND: Cannabidiol, which is one of the main cannabinoids present in Cannabis sativa plants, has been shown to have therapeutic properties, including anti-inflammatory and antioxidant effects that may be useful for treatment of various kidney conditions. ...CON …
BACKGROUND: Cannabidiol, which is one of the main cannabinoids present in Cannabis sativa plants, has been shown to have therapeutic …
Adenosine-Related Mechanisms in Non-Adenosine Receptor Drugs.
Jacobson KA, Reitman ML. Jacobson KA, et al. Cells. 2020 Apr 13;9(4):956. doi: 10.3390/cells9040956. Cells. 2020. PMID: 32295065 Free PMC article. Review.
Non-AR mechanisms include raising adenosine levels by inhibiting adenosine transport (e.g., ticagrelor, ethanol, and cannabidiol), affecting intracellular metabolic pathways (e.g., methotrexate, nicotinamide riboside, salicylate, and 5-aminoimidazole-4-carboxamide riboside …
Non-AR mechanisms include raising adenosine levels by inhibiting adenosine transport (e.g., ticagrelor, ethanol, and cannabidiol), af …
The effects of Cannabidiol on podocytes in vitro.
Didik S, Ahrari A, Taneja K, Bohovyk R, Levchenko V, Dissanayake LV, O-Uchi J, Staruschenko A. Didik S, et al. Biochem Biophys Res Commun. 2025 Oct 10;784:152654. doi: 10.1016/j.bbrc.2025.152654. Epub 2025 Sep 14. Biochem Biophys Res Commun. 2025. PMID: 40967036 Free PMC article.
Cannabidiol (CBD) is a popular non-psychoactive formulation commonly used to treat pain, anxiety, and nausea. ...Importantly, our results suggest that high-dose, long-term CBD exposure may compromise podocyte health and potentially impair kidney function....
Cannabidiol (CBD) is a popular non-psychoactive formulation commonly used to treat pain, anxiety, and nausea. ...Importantly, our res …
CBGA ameliorates inflammation and fibrosis in nephropathy.
Suzuki S, Fleig A, Penner R. Suzuki S, et al. Sci Rep. 2023 Apr 18;13(1):6341. doi: 10.1038/s41598-023-33507-2. Sci Rep. 2023. PMID: 37072467 Free PMC article.
The endocannabinoid system has recently emerged to contribute to kidney disease, however, the therapeutic properties of cannabinoids in kidney disease remain largely unknown. In this study, we determined whether CBD and CBGA can attenuate kidney …
The endocannabinoid system has recently emerged to contribute to kidney disease, however, the therapeutic properties of cannab …
The effects of cannabinoids on the kidney.
Didik S, Palygin O, Chandy M, Staruschenko A. Didik S, et al. Acta Physiol (Oxf). 2024 Dec;240(12):e14247. doi: 10.1111/apha.14247. Epub 2024 Oct 24. Acta Physiol (Oxf). 2024. PMID: 39445706 Free PMC article. Review.
Following, we briefly discuss the role of the ECS in various kidney diseases and the potential therapeutic applications of drugs targeting the cannabinoid system. Lastly, recent studies have identified several detrimental effects of cannabinoids, not only on the …
Following, we briefly discuss the role of the ECS in various kidney diseases and the potential therapeutic applications of dru …
The nephrologist's guide to cannabis and cannabinoids.
Rein JL. Rein JL. Curr Opin Nephrol Hypertens. 2020 Mar;29(2):248-257. doi: 10.1097/MNH.0000000000000590. Curr Opin Nephrol Hypertens. 2020. PMID: 31972598 Free PMC article. Review.
RECENT FINDINGS: Cannabis may have medicinal benefits for treating symptoms of advanced chronic kidney disease (CKD) and end-stage renal disease including as a pain adjuvant potentially reducing the need for opioids. ...SUMMARY: Patients and healthcare profes …
RECENT FINDINGS: Cannabis may have medicinal benefits for treating symptoms of advanced chronic kidney disease (CKD) and end-s …
Cannabidiol Enhances the Therapeutic Efficacy of Olsalazine and Cyclosporine in a Murine Model of Colitis.
Thapa D, Patil M, Warne LN, Carlessi R, Falasca M. Thapa D, et al. Int J Mol Sci. 2025 Aug 16;26(16):7913. doi: 10.3390/ijms26167913. Int J Mol Sci. 2025. PMID: 40869234 Free PMC article.
Current therapies for inflammatory bowel disease (IBD), such as olsalazine and cyclosporine, often exhibit limited long-term efficacy and are associated with adverse effects. Cannabidiol (CBD), a non-psychoactive phytocannabinoid, shows promise for its anti-inflamma …
Current therapies for inflammatory bowel disease (IBD), such as olsalazine and cyclosporine, often exhibit limited long-term efficacy …
54 results