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Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition in Vivo.
Lorthiois E, Anderson K, Vulpetti A, Rogel O, Cumin F, Ostermann N, Steinbacher S, Mac Sweeney A, Delgado O, Liao SM, Randl S, Rüdisser S, Dussauge S, Fettis K, Kieffer L, de Erkenez A, Yang L, Hartwieg C, Argikar UA, La Bonte LR, Newton R, Kansara V, Flohr S, Hommel U, Jaffee B, Maibaum J. Lorthiois E, et al. Among authors: kieffer l. J Med Chem. 2017 Jul 13;60(13):5717-5735. doi: 10.1021/acs.jmedchem.7b00425. Epub 2017 Jun 30. J Med Chem. 2017. PMID: 28621538
Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood.
Quancard J, Simic O, Pissot Soldermann C, Aichholz R, Blatter M, Renatus M, Erbel P, Melkko S, Endres R, Sorge M, Kieffer L, Wagner T, Beltz K, Mcsheehy P, Wartmann M, Régnier CH, Calzascia T, Radimerski T, Bigaud M, Weiss A, Bornancin F, Schlapbach A. Quancard J, et al. Among authors: kieffer l. J Med Chem. 2020 Dec 10;63(23):14594-14608. doi: 10.1021/acs.jmedchem.0c01246. Epub 2020 Nov 20. J Med Chem. 2020. PMID: 33216547
Azaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5.
Altmann E, Erbel P, Renatus M, Schaefer M, Schlierf A, Druet A, Kieffer L, Sorge M, Pfister K, Hassiepen U, Jones M, Ruedisser S, Ostermeier D, Martoglio B, Jefferson AB, Quancard J. Altmann E, et al. Among authors: kieffer l. Angew Chem Int Ed Engl. 2017 Jan 24;56(5):1294-1297. doi: 10.1002/anie.201608672. Epub 2016 Dec 16. Angew Chem Int Ed Engl. 2017. PMID: 27981705
Program Factors Affecting Weight Loss and Mobility in Older Adults: Evidence From the Mobility and Vitality Lifestyle Program (MOVE UP).
Liu X, Kieffer LA, King J, Boak B, Zgibor JC, Smith KJ, Burke LE, Jakicic JM, Semler LN, Danielson ME, Newman AB, Venditti EM, Albert SM. Liu X, et al. Among authors: kieffer la. Health Promot Pract. 2023 Mar 28:15248399231162377. doi: 10.1177/15248399231162377. Online ahead of print. Health Promot Pract. 2023. PMID: 36975377
Weight Loss through Lifestyle Intervention Improves Mobility in Older Adults.
Albert SM, Venditti EM, Boudreau RM, Kieffer LA, Rager JR, Zgibor JC, Vander Bilt J, Danielson ME, Burke LE, Glynn NW, Jakicic JM, Smith KJ, Semler LN, Newman AB. Albert SM, et al. Among authors: kieffer la. Gerontologist. 2022 Jul 15;62(6):931-941. doi: 10.1093/geront/gnab048. Gerontologist. 2022. PMID: 33822933 Free PMC article.
Mobility and Vitality Lifestyle Program (MOVE UP): A Community Health Worker Intervention for Older Adults With Obesity to Improve Weight, Health, and Physical Function.
Venditti EM, Zgibor JC, Vander Bilt J, Kieffer LA, Boudreau RM, Burke LE, Glynn NW, Jakicic JM, Smith KJ, Semler LN, Rager JR, Albert SM, Newman AB. Venditti EM, et al. Among authors: kieffer la. Innov Aging. 2018 Jun 18;2(2):igy012. doi: 10.1093/geroni/igy012. eCollection 2018 Jun. Innov Aging. 2018. PMID: 30480135 Free PMC article.
A survey of practice patterns for rehabilitation post elbow fracture.
Macdermid JC, Vincent JI, Kieffer L, Kieffer A, Demaiter J, Macintosh S. Macdermid JC, et al. Among authors: kieffer l. Open Orthop J. 2012;6:429-39. doi: 10.2174/1874325001206010429. Epub 2012 Oct 2. Open Orthop J. 2012. PMID: 23115603 Free PMC article.
30 results