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SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.
Ziegler CGK, Allon SJ, Nyquist SK, Mbano IM, Miao VN, Tzouanas CN, Cao Y, Yousif AS, Bals J, Hauser BM, Feldman J, Muus C, Wadsworth MH 2nd, Kazer SW, Hughes TK, Doran B, Gatter GJ, Vukovic M, Taliaferro F, Mead BE, Guo Z, Wang JP, Gras D, Plaisant M, Ansari M, Angelidis I, Adler H, Sucre JMS, Taylor CJ, Lin B, Waghray A, Mitsialis V, Dwyer DF, Buchheit KM, Boyce JA, Barrett NA, Laidlaw TM, Carroll SL, Colonna L, Tkachev V, Peterson CW, Yu A, Zheng HB, Gideon HP, Winchell CG, Lin PL, Bingle CD, Snapper SB, Kropski JA, Theis FJ, Schiller HB, Zaragosi LE, Barbry P, Leslie A, Kiem HP, Flynn JL, Fortune SM, Berger B, Finberg RW, Kean LS, Garber M, Schmidt AG, Lingwood D, Shalek AK, Ordovas-Montanes J; HCA Lung Biological Network. Electronic address: lung-network@humancellatlas.org; HCA Lung Biological Network. Ziegler CGK, et al. Among authors: Kiem HP. Cell. 2020 Apr 27:S0092-8674(20)30500-6. doi: 10.1016/j.cell.2020.04.035. Online ahead of print. Cell. 2020. PMID: 32413319 Free article.
DNA Barcoding in Nonhuman Primates Reveals Important Limitations in Retrovirus Integration Site Analysis.
Adair JE, Enstrom MR, Haworth KG, Schefter LE, Shahbazi R, Humphrys DR, Porter S, Tam K, Porteus MH, Kiem HP. Adair JE, et al. Among authors: Kiem HP. Mol Ther Methods Clin Dev. 2020 Mar 30;17:796-809. doi: 10.1016/j.omtm.2020.03.021. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32355868 Free PMC article.
The evolution of viral integration site analysis.
Radtke S, Kiem HP. Radtke S, et al. Among authors: Kiem HP. Blood. 2020 Apr 9;135(15):1192-1193. doi: 10.1182/blood.2020005115. Blood. 2020. PMID: 32271907 Free PMC article.
HLA-Haploidentical Hematopoietic Cell Transplantation for Treatment of Nonmalignant Diseases Using Nonmyeloablative Conditioning and Post-Transplant Cyclophosphamide.
Mallhi KK, Srikanthan MA, Baker KK, Frangoul HA, Torgerson TR, Petrovic A, Geddis AE, Carpenter PA, Baker KS, Sandmaier BM, Thakar MS, Skoda-Smith S, Kiem HP, Storb R, Woolfrey AE, Burroughs LM. Mallhi KK, et al. Among authors: Kiem HP. Biol Blood Marrow Transplant. 2020 Mar 28:S1083-8791(20)30176-2. doi: 10.1016/j.bbmt.2020.03.018. Online ahead of print. Biol Blood Marrow Transplant. 2020. PMID: 32234377
Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning.
Srikanthan MA, Humbert O, Haworth KG, Ironside C, Rajawat YS, Blazar BR, Palchaudhuri R, Boitano AE, Cooke MP, Scadden DT, Kiem HP. Srikanthan MA, et al. Among authors: Kiem HP. Mol Ther Methods Clin Dev. 2020 Feb 8;17:455-464. doi: 10.1016/j.omtm.2020.02.001. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32226796 Free PMC article.
The CD33 splice isoform lacking exon 2 as therapeutic target in human acute myeloid leukemia.
Godwin CD, Laszlo GS, Wood BL, Correnti CE, Bates OM, Garling EE, Mao ZJ, Beddoe ME, Lunn MC, Humbert O, Kiem HP, Walter RB. Godwin CD, et al. Among authors: Kiem HP. Leukemia. 2020 Feb 18. doi: 10.1038/s41375-020-0755-7. Online ahead of print. Leukemia. 2020. PMID: 32071429 No abstract available.
Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy.
Sheih A, Voillet V, Hanafi LA, DeBerg HA, Yajima M, Hawkins R, Gersuk V, Riddell SR, Maloney DG, Wohlfahrt ME, Pande D, Enstrom MR, Kiem HP, Adair JE, Gottardo R, Linsley PS, Turtle CJ. Sheih A, et al. Among authors: Kiem HP. Nat Commun. 2020 Jan 10;11(1):219. doi: 10.1038/s41467-019-13880-1. Nat Commun. 2020. PMID: 31924795 Free PMC article. Clinical Trial.
In-Vivo Gene Therapy with Foamy Virus Vectors.
Rajawat YS, Humbert O, Kiem HP. Rajawat YS, et al. Among authors: Kiem HP. Viruses. 2019 Nov 23;11(12):1091. doi: 10.3390/v11121091. Viruses. 2019. PMID: 31771194 Free PMC article. Review.
Mouse models in hematopoietic stem cell gene therapy and genome editing.
Radtke S, Humbert O, Kiem HP. Radtke S, et al. Among authors: Kiem HP. Biochem Pharmacol. 2020 Apr;174:113692. doi: 10.1016/j.bcp.2019.113692. Epub 2019 Nov 6. Biochem Pharmacol. 2020. PMID: 31705854 Review.
Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes.
Ozog S, Timberlake ND, Hermann K, Garijo O, Haworth KG, Shi G, Glinkerman CM, Schefter LE, D'Souza S, Simpson E, Sghia-Hughes G, Carillo RR, Boger DL, Kiem HP, Slukvin I, Ryu BY, Sorrentino BP, Adair JE, Snyder SA, Compton AA, Torbett BE. Ozog S, et al. Among authors: Kiem HP. Blood. 2019 Oct 17;134(16):1298-1311. doi: 10.1182/blood.2019000040. Blood. 2019. PMID: 31416800
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