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Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies.
Brennan FR, Morton LD, Spindeldreher S, Kiessling A, Allenspach R, Hey A, Muller PY, Frings W, Sims J. Brennan FR, et al. Among authors: kiessling a. MAbs. 2010 May-Jun;2(3):233-55. doi: 10.4161/mabs.2.3.11782. Epub 2010 May 23. MAbs. 2010. PMID: 20421713 Free PMC article. Review.
Aggregation of human recombinant monoclonal antibodies influences the capacity of dendritic cells to stimulate adaptive T-cell responses in vitro.
Rombach-Riegraf V, Karle AC, Wolf B, Sordé L, Koepke S, Gottlieb S, Krieg J, Djidja MC, Baban A, Spindeldreher S, Koulov AV, Kiessling A. Rombach-Riegraf V, et al. Among authors: kiessling a. PLoS One. 2014 Jan 21;9(1):e86322. doi: 10.1371/journal.pone.0086322. eCollection 2014. PLoS One. 2014. PMID: 24466023 Free PMC article.
Response to the letter to the editor by Susan Thorpe et al.: how predictive are in vitro assays for cytokine release syndrome in vivo? A comparison of methods reveals worrying differences in sensitivity and frequency of response.
Wolf B, Morgan H, Brennan F, Krieg J, Gani Z, Jones S, Kiessling A. Wolf B, et al. Among authors: kiessling a. Cytokine. 2013 Oct;64(1):473-5; discussion 476. doi: 10.1016/j.cyto.2013.07.014. Epub 2013 Aug 3. Cytokine. 2013. PMID: 23921146 No abstract available.
Biotherapeutics in non-clinical development: Strengthening the interface between safety, pharmacokinetics-pharmacodynamics and manufacturing.
Ulrich P, Blaich G, Baumann A, Fagg R, Hey A, Kiessling A, Kronenberg S, Lindecrona RH, Mohl S, Richter WF, Tibbitts J, Crameri F, Weir L. Ulrich P, et al. Among authors: kiessling a. Regul Toxicol Pharmacol. 2018 Apr;94:91-100. doi: 10.1016/j.yrtph.2018.01.013. Epub 2018 Jan 28. Regul Toxicol Pharmacol. 2018. PMID: 29355662
Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration.
Smith B, Kiessling A, Lledo-Garcia R, Dixon KL, Christodoulou L, Catley MC, Atherfold P, D'Hooghe LE, Finney H, Greenslade K, Hailu H, Kevorkian L, Lightwood D, Meier C, Munro R, Qureshi O, Sarkar K, Shaw SP, Tewari R, Turner A, Tyson K, West S, Shaw S, Brennan FR. Smith B, et al. Among authors: kiessling a. MAbs. 2018 Oct;10(7):1111-1130. doi: 10.1080/19420862.2018.1505464. Epub 2018 Sep 12. MAbs. 2018. PMID: 30130439 Free PMC article.
308 results