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Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene.
Kleymenova E, Ibraghimov-Beskrovnaya O, Kugoh H, Everitt J, Xu H, Kiguchi K, Landes G, Harris P, Walker C. Kleymenova E, et al. Mol Cell. 2001 Apr;7(4):823-32. doi: 10.1016/s1097-2765(01)00226-x. Mol Cell. 2001. PMID: 11336705
WWOX, the FRA16D gene, behaves as a suppressor of tumor growth.
Bednarek AK, Keck-Waggoner CL, Daniel RL, Laflin KJ, Bergsagel PL, Kiguchi K, Brenner AJ, Aldaz CM. Bednarek AK, et al. Cancer Res. 2001 Nov 15;61(22):8068-73. Cancer Res. 2001. PMID: 11719429
Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.
Kiguchi K, Bol D, Carbajal S, Beltrán L, Moats S, Chan K, Jorcano J, DiGiovanni J. Kiguchi K, et al. Oncogene. 2000 Aug 31;19(37):4243-54. doi: 10.1038/sj.onc.1203778. Oncogene. 2000. PMID: 10980598
Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion.
DiGiovanni J, Bol DK, Wilker E, Beltrán L, Carbajal S, Moats S, Ramirez A, Jorcano J, Kiguchi K. DiGiovanni J, et al. Cancer Res. 2000 Mar 15;60(6):1561-70. Cancer Res. 2000. PMID: 10749124
Deregulated expression of insulin-like growth factor 1 in prostate epithelium leads to neoplasia in transgenic mice.
DiGiovanni J, Kiguchi K, Frijhoff A, Wilker E, Bol DK, Beltrán L, Moats S, Ramirez A, Jorcano J, Conti C. DiGiovanni J, et al. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3455-60. doi: 10.1073/pnas.97.7.3455. Proc Natl Acad Sci U S A. 2000. PMID: 10737798 Free PMC article.
Enhancement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice.
Wilker E, Bol D, Kiguchi K, Rupp T, Beltrán L, DiGiovanni J. Wilker E, et al. Mol Carcinog. 1999 Jun;25(2):122-31. doi: 10.1002/(sici)1098-2744(199906)25:2<122::aid-mc7>3.0.co;2-8. Mol Carcinog. 1999. PMID: 10365914
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