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An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls.
Okamoto Y, Arita Y, Nishida M, Muraguchi M, Ouchi N, Takahashi M, Igura T, Inui Y, Kihara S, Nakamura T, Yamashita S, Miyagawa J, Funahashi T, Matsuzawa Y. Okamoto Y, et al. Among authors: kihara s. Horm Metab Res. 2000 Feb;32(2):47-50. doi: 10.1055/s-2007-978586. Horm Metab Res. 2000. PMID: 10741683
Effect of pravastatin on the development of diabetes and adiponectin production.
Takagi T, Matsuda M, Abe M, Kobayashi H, Fukuhara A, Komuro R, Kihara S, Caslake MJ, McMahon A, Shepherd J, Funahashi T, Shimomura I. Takagi T, et al. Among authors: kihara s. Atherosclerosis. 2008 Jan;196(1):114-121. doi: 10.1016/j.atherosclerosis.2007.02.013. Epub 2007 Mar 27. Atherosclerosis. 2008. PMID: 17391675
Adiponectin inhibits endothelial synthesis of interleukin-8.
Kobashi C, Urakaze M, Kishida M, Kibayashi E, Kobayashi H, Kihara S, Funahashi T, Takata M, Temaru R, Sato A, Yamazaki K, Nakamura N, Kobayashi M. Kobashi C, et al. Among authors: kihara s. Circ Res. 2005 Dec 9;97(12):1245-52. doi: 10.1161/01.RES.0000194328.57164.36. Epub 2005 Nov 3. Circ Res. 2005. PMID: 16269654
Adiponectin prevents atherosclerosis by increasing cholesterol efflux from macrophages.
Tsubakio-Yamamoto K, Matsuura F, Koseki M, Oku H, Sandoval JC, Inagaki M, Nakatani K, Nakaoka H, Kawase R, Yuasa-Kawase M, Masuda D, Ohama T, Maeda N, Nakagawa-Toyama Y, Ishigami M, Nishida M, Kihara S, Shimomura I, Yamashita S. Tsubakio-Yamamoto K, et al. Among authors: kihara s. Biochem Biophys Res Commun. 2008 Oct 24;375(3):390-4. doi: 10.1016/j.bbrc.2008.08.009. Epub 2008 Aug 12. Biochem Biophys Res Commun. 2008. PMID: 18703020
URB is abundantly expressed in adipose tissue and dysregulated in obesity.
Okada T, Nishizawa H, Kurata A, Tamba S, Sonoda M, Yasui A, Kuroda Y, Hibuse T, Maeda N, Kihara S, Hadama T, Tobita K, Akamatsu S, Maeda K, Shimomura I, Funahashi T. Okada T, et al. Among authors: kihara s. Biochem Biophys Res Commun. 2008 Mar 7;367(2):370-6. doi: 10.1016/j.bbrc.2007.12.164. Epub 2008 Jan 4. Biochem Biophys Res Commun. 2008. PMID: 18178152
Effects of peroxisome proliferator-activated receptor ligands, bezafibrate and fenofibrate, on adiponectin level.
Hiuge A, Tenenbaum A, Maeda N, Benderly M, Kumada M, Fisman EZ, Tanne D, Matas Z, Hibuse T, Fujita K, Nishizawa H, Adler Y, Motro M, Kihara S, Shimomura I, Behar S, Funahashi T. Hiuge A, et al. Among authors: kihara s. Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):635-41. doi: 10.1161/01.ATV.0000256469.06782.d5. Epub 2006 Dec 28. Arterioscler Thromb Vasc Biol. 2007. PMID: 17194889 Clinical Trial.
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