Kilpatrick AT - Search Results

1

Structure-affinity relationships of 12-sulfonyl derivatives of 5,8,8a,9,10,11,12,12a,13,13a-decahydro-6H-isoquino[2,1-g][1 ,6] naphthyridines at alpha-adrenoceptors.

Clark RD, Repke DB, Berger J, Nelson JT, Kilpatrick AT, Brown CM, MacKinnon AC, Clague RU, Spedding M. Clark RD, et al. Among authors: kilpatrick at. J Med Chem. 1991 Feb;34(2):705-17. doi: 10.1021/jm00106a036. J Med Chem. 1991. PMID: 1671705

2

[3H]-RS-15385-197, a selective and high affinity radioligand for alpha 2-adrenoceptors: implications for receptor classification.

MacKinnon AC, Kilpatrick AT, Kenny BA, Spedding M, Brown CM. MacKinnon AC, et al. Among authors: kilpatrick at. Br J Pharmacol. 1992 Aug;106(4):1011-8. doi: 10.1111/j.1476-5381.1992.tb14449.x. Br J Pharmacol. 1992. PMID: 1327384 Free PMC article.

3

Heterogeneity of alpha 2-adrenoceptors in rat cortex but not human platelets can be defined by 8-OH-DPAT, RU 24969 and methysergide.

Brown CM, MacKinnon AC, McGrath JC, Spedding M, Kilpatrick AT. Brown CM, et al. Among authors: kilpatrick at. Br J Pharmacol. 1990 Mar;99(3):481-6. doi: 10.1111/j.1476-5381.1990.tb12954.x. Br J Pharmacol. 1990. PMID: 1970497 Free PMC article.

4

Alpha 2-adrenoceptor subtypes and imidazoline-like binding sites in the rat brain.

Brown CM, MacKinnon AC, McGrath JC, Spedding M, Kilpatrick AT. Brown CM, et al. Among authors: kilpatrick at. Br J Pharmacol. 1990 Apr;99(4):803-9. doi: 10.1111/j.1476-5381.1990.tb13010.x. Br J Pharmacol. 1990. PMID: 1972896 Free PMC article.

5

Affinity of 2-(tetrahydroisoquinolin-2-ylmethyl)- and 2-(isoindolin-2-ylmethyl)imidazolines for alpha-adrenoceptors. Differential affinity of imidazolines for the [3H]idazoxan-labeled alpha 2-adrenoceptor vs the [3H]yohimbine-labeled site.

Clark RD, Berger J, Garg P, Weinhardt KK, Spedding M, Kilpatrick AT, Brown CM, MacKinnon AC. Clark RD, et al. Among authors: kilpatrick at. J Med Chem. 1990 Feb;33(2):596-600. doi: 10.1021/jm00164a021. J Med Chem. 1990. PMID: 2153820

6

1,9-Alkano-bridged 2,3,4,5-tetrahydro-1H-3-benzazepines with affinity for the alpha 2-adrenoceptor and the 5-HT1A receptor.

Clark RD, Weinhardt KK, Berger J, Fisher LE, Brown CM, MacKinnon AC, Kilpatrick AT, Spedding M. Clark RD, et al. Among authors: kilpatrick at. J Med Chem. 1990 Feb;33(2):633-41. doi: 10.1021/jm00164a026. J Med Chem. 1990. PMID: 2153822

7

(8a alpha,12a alpha,13a alpha)-5,8,8a,9,10,11,12,12a,13,13a-decahydro- 3-methoxy-12-(methylsulfonyl)-6H-isoquino[2,1-g][1,6]naphthyridi ne, a potent and highly selective alpha 2-adrenoceptor antagonist.

Clark RD, Repke DB, Kilpatrick AT, Brown CM, MacKinnon AC, Clague RU, Spedding M. Clark RD, et al. Among authors: kilpatrick at. J Med Chem. 1989 Sep;32(9):2034-6. doi: 10.1021/jm00129a002. J Med Chem. 1989. PMID: 2570150 No abstract available.

8

The alpha 2-adrenoceptor antagonist SK&F 104078 has high affinity for 5-HT1A and 5-HT2 receptors.

Kilpatrick AT, Brown CM, MacKinnon AC, Spedding M. Kilpatrick AT, et al. Eur J Pharmacol. 1989 Jul 18;166(2):315-8. doi: 10.1016/0014-2999(89)90075-7. Eur J Pharmacol. 1989. PMID: 2571511

9

The pharmacology of RS-15385-197, a potent and selective alpha 2-adrenoceptor antagonist.

Brown CM, MacKinnon AC, Redfern WS, Hicks PE, Kilpatrick AT, Small C, Ramcharan M, Clague RU, Clark RD, MacFarlane CB, et al. Brown CM, et al. Among authors: kilpatrick at. Br J Pharmacol. 1993 Feb;108(2):516-25. doi: 10.1111/j.1476-5381.1993.tb12834.x. Br J Pharmacol. 1993. PMID: 8095420 Free PMC article.

10

Modulation of central noradrenergic function by RS-15385-197.

Redfern WS, MacKinnon AC, Brown CM, Martin AB, Kilpatrick AT, Clague RU, Spedding M. Redfern WS, et al. Among authors: kilpatrick at. Br J Pharmacol. 1993 Feb;108(2):526-33. doi: 10.1111/j.1476-5381.1993.tb12835.x. Br J Pharmacol. 1993. PMID: 8095421 Free PMC article.

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