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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Sarbassov DD, et al. Among authors: kim dh. Curr Biol. 2004 Jul 27;14(14):1296-302. doi: 10.1016/j.cub.2004.06.054. Curr Biol. 2004. PMID: 15268862
mTOR regulation of autophagy.
Jung CH, Ro SH, Cao J, Otto NM, Kim DH. Jung CH, et al. Among authors: kim dh. FEBS Lett. 2010 Apr 2;584(7):1287-95. doi: 10.1016/j.febslet.2010.01.017. Epub 2010 Jan 18. FEBS Lett. 2010. PMID: 20083114 Free PMC article. Review.
Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb.
Lee MN, Ha SH, Kim J, Koh A, Lee CS, Kim JH, Jeon H, Kim DH, Suh PG, Ryu SH. Lee MN, et al. Among authors: kim j, kim jh, kim dh. Mol Cell Biol. 2009 Jul;29(14):3991-4001. doi: 10.1128/MCB.00165-09. Epub 2009 May 18. Mol Cell Biol. 2009. PMID: 19451232 Free PMC article.
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.
Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, Cao J, Kundu M, Kim DH. Jung CH, et al. Among authors: kim ym, kim dh. Mol Biol Cell. 2009 Apr;20(7):1992-2003. doi: 10.1091/mbc.e08-12-1249. Epub 2009 Feb 18. Mol Biol Cell. 2009. PMID: 19225151 Free PMC article.
PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
Woo SY, Kim DH, Jun CB, Kim YM, Haar EV, Lee SI, Hegg JW, Bandhakavi S, Griffin TJ, Kim DH. Woo SY, et al. Among authors: kim dh, kim ym, kim dh. J Biol Chem. 2007 Aug 31;282(35):25604-12. doi: 10.1074/jbc.M704343200. Epub 2007 Jun 28. J Biol Chem. 2007. PMID: 17599906
Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40.
Vander Haar E, Lee SI, Bandhakavi S, Griffin TJ, Kim DH. Vander Haar E, et al. Among authors: kim dh. Nat Cell Biol. 2007 Mar;9(3):316-23. doi: 10.1038/ncb1547. Epub 2007 Feb 4. Nat Cell Biol. 2007. PMID: 17277771
PLD2 forms a functional complex with mTOR/raptor to transduce mitogenic signals.
Ha SH, Kim DH, Kim IS, Kim JH, Lee MN, Lee HJ, Kim JH, Jang SK, Suh PG, Ryu SH. Ha SH, et al. Among authors: kim dh, kim is, kim jh, kim jh. Cell Signal. 2006 Dec;18(12):2283-91. doi: 10.1016/j.cellsig.2006.05.021. Epub 2006 Jun 3. Cell Signal. 2006. PMID: 16837165
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.
Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Kim DH, et al. Cell. 2002 Jul 26;110(2):163-75. doi: 10.1016/s0092-8674(02)00808-5. Cell. 2002. PMID: 12150925
GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR.
Kim DH, Sarbassov DD, Ali SM, Latek RR, Guntur KV, Erdjument-Bromage H, Tempst P, Sabatini DM. Kim DH, et al. Mol Cell. 2003 Apr;11(4):895-904. doi: 10.1016/s1097-2765(03)00114-x. Mol Cell. 2003. PMID: 12718876
Down regulation of Peroxiredoxin-3 in 3T3-L1 adipocytes leads to oxidation of Rictor in the mammalian-target of rapamycin complex 2 (mTORC2).
Olson DH, Burrill JS, Kuzmicic J, Hahn WS, Park JM, Kim DH, Bernlohr DA. Olson DH, et al. Among authors: kim dh. Biochem Biophys Res Commun. 2017 Nov 25;493(3):1311-1317. doi: 10.1016/j.bbrc.2017.09.171. Epub 2017 Oct 3. Biochem Biophys Res Commun. 2017. PMID: 28986255
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