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Chromothripsis drives the evolution of gene amplification in cancer.
Shoshani O, Brunner SF, Yaeger R, Ly P, Nechemia-Arbely Y, Kim DH, Fang R, Castillon GA, Yu M, Li JSZ, Sun Y, Ellisman MH, Ren B, Campbell PJ, Cleveland DW. Shoshani O, et al. Among authors: kim dh. Nature. 2021 Mar;591(7848):137-141. doi: 10.1038/s41586-020-03064-z. Epub 2020 Dec 23. Nature. 2021. PMID: 33361815 Free PMC article.
Transient genomic instability drives tumorigenesis through accelerated clonal evolution.
Shoshani O, Bakker B, de Haan L, Tijhuis AE, Wang Y, Kim DH, Maldonado M, Demarest MA, Artates J, Zhengyu O, Mark A, Wardenaar R, Sasik R, Spierings DCJ, Vitre B, Fisch K, Foijer F, Cleveland DW. Shoshani O, et al. Among authors: kim dh. Genes Dev. 2021 Aug 1;35(15-16):1093-1108. doi: 10.1101/gad.348319.121. Epub 2021 Jul 15. Genes Dev. 2021. PMID: 34266887 Free PMC article.
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