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Insights into the connection between cancer and alternative splicing.
Kim E, Goren A, Ast G. Kim E, et al. Trends Genet. 2008 Jan;24(1):7-10. doi: 10.1016/j.tig.2007.10.001. Epub 2007 Dec 3. Trends Genet. 2008. PMID: 18054115
Overlapping splicing regulatory motifs--combinatorial effects on splicing.
Goren A, Kim E, Amit M, Vaknin K, Kfir N, Ram O, Ast G. Goren A, et al. Nucleic Acids Res. 2010 Jun;38(10):3318-27. doi: 10.1093/nar/gkq005. Epub 2010 Jan 27. Nucleic Acids Res. 2010. PMID: 20110253 Free PMC article.
Intronic Alus influence alternative splicing.
Lev-Maor G, Ram O, Kim E, Sela N, Goren A, Levanon EY, Ast G. Lev-Maor G, et al. PLoS Genet. 2008 Sep 26;4(9):e1000204. doi: 10.1371/journal.pgen.1000204. PLoS Genet. 2008. PMID: 18818740 Free PMC article.
The "alternative" choice of constitutive exons throughout evolution.
Lev-Maor G, Goren A, Sela N, Kim E, Keren H, Doron-Faigenboim A, Leibman-Barak S, Pupko T, Ast G. Lev-Maor G, et al. PLoS Genet. 2007 Nov;3(11):e203. doi: 10.1371/journal.pgen.0030203. PLoS Genet. 2007. PMID: 18020709 Free PMC article.
Different levels of alternative splicing among eukaryotes.
Kim E, Magen A, Ast G. Kim E, et al. Nucleic Acids Res. 2007;35(1):125-31. doi: 10.1093/nar/gkl924. Epub 2006 Dec 7. Nucleic Acids Res. 2007. PMID: 17158149 Free PMC article.
Differential GC content between exons and introns establishes distinct strategies of splice-site recognition.
Amit M, Donyo M, Hollander D, Goren A, Kim E, Gelfman S, Lev-Maor G, Burstein D, Schwartz S, Postolsky B, Pupko T, Ast G. Amit M, et al. Cell Rep. 2012 May 31;1(5):543-56. doi: 10.1016/j.celrep.2012.03.013. Epub 2012 May 3. Cell Rep. 2012. PMID: 22832277
Alu exonization events reveal features required for precise recognition of exons by the splicing machinery.
Schwartz S, Gal-Mark N, Kfir N, Oren R, Kim E, Ast G. Schwartz S, et al. PLoS Comput Biol. 2009 Mar;5(3):e1000300. doi: 10.1371/journal.pcbi.1000300. Epub 2009 Mar 6. PLoS Comput Biol. 2009. PMID: 19266014 Free PMC article.
Alternative splicing and disease.
Kim E, Goren A, Ast G. Kim E, et al. RNA Biol. 2008 Jan-Mar;5(1):17-9. doi: 10.4161/rna.5.1.5944. Epub 2008 Mar 22. RNA Biol. 2008. PMID: 18388487
Alternative splicing: current perspectives.
Kim E, Goren A, Ast G. Kim E, et al. Bioessays. 2008 Jan;30(1):38-47. doi: 10.1002/bies.20692. Bioessays. 2008. PMID: 18081010 Review.
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