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Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage.
Kang ES, Woo IS, Kim HJ, Eun SY, Paek KS, Kim HJ, Chang KC, Lee JH, Lee HT, Kim JH, Nishinaka T, Yabe-Nishimura C, Seo HG. Kang ES, et al. Among authors: kim hj, kim jh. Free Radic Biol Med. 2007 Aug 15;43(4):535-45. doi: 10.1016/j.freeradbiomed.2007.05.006. Epub 2007 May 16. Free Radic Biol Med. 2007. PMID: 17640564
Peroxisome proliferator-activated receptor {delta} regulates extracellular matrix and apoptosis of vascular smooth muscle cells through the activation of transforming growth factor-{beta}1/Smad3.
Kim HJ, Kim MY, Jin H, Kim HJ, Kang SS, Kim HJ, Lee JH, Chang KC, Hwang JY, Yabe-Nishimura C, Kim JH, Seo HG. Kim HJ, et al. Among authors: kim my, kim jh. Circ Res. 2009 Jul 2;105(1):16-24. doi: 10.1161/CIRCRESAHA.108.189159. Epub 2009 May 21. Circ Res. 2009. PMID: 19461048
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