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Discovery of 2-((R)-4-(2-Fluoro-4-(methylsulfonyl)phenyl)-2-methylpiperazin-1-yl)-N-((1R,2s,3S,5S,7S)-5-hydroxyadamantan-2-yl)pyrimidine-4-carboxamide (SKI2852): A Highly Potent, Selective, and Orally Bioavailable Inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1).
Ryu JH, Lee JA, Kim S, Shin YA, Yang J, Han HY, Son HJ, Kim YH, Sa JH, Kim JS, Lee J, Lee J, Park HG. Ryu JH, et al. Among authors: kim yh, kim s, kim js. J Med Chem. 2016 Nov 23;59(22):10176-10189. doi: 10.1021/acs.jmedchem.6b01122. Epub 2016 Nov 7. J Med Chem. 2016. PMID: 27798827
Analysis of Response and Progression Patterns of Tyrosine Kinase Inhibitors in Recurrent or Metastatic Adenoid Cystic Carcinoma: A Post Hoc Analysis of Two KCSG Phase II Trials.
Kim Y, Keam B, Kang EJ, Kim JS, Kim HR, Lee KW, Kwon JH, Lee KE, Yang Y, Choi YH, Kim MK, Ji JH, Yun T, Choi MY, Lee KH, Kim SB, Ahn MJ. Kim Y, et al. Among authors: kim js. Cancer Res Treat. 2024 Apr 15. doi: 10.4143/crt.2024.008. Online ahead of print. Cancer Res Treat. 2024. PMID: 38637966
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