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An aqueous extract of Salacia oblonga root, a herb-derived peroxisome proliferator-activated receptor-alpha activator, by oral gavage over 28 days induces gender-dependent hepatic hypertrophy in rats.
Rong X, Kim MS, Su N, Wen S, Matsuo Y, Yamahara J, Murray M, Li Y. Rong X, et al. Food Chem Toxicol. 2008 Jun;46(6):2165-72. doi: 10.1016/j.fct.2008.02.022. Epub 2008 Mar 4. Food Chem Toxicol. 2008. PMID: 18397819
Compound K modulates fatty acid-induced lipid droplet formation and expression of proteins involved in lipid metabolism in hepatocytes.
Kim MS, Lee KT, Iseli TJ, Hoy AJ, George J, Grewal T, Roufogalis BD. Kim MS, et al. Liver Int. 2013 Nov;33(10):1583-93. doi: 10.1111/liv.12287. Epub 2013 Sep 2. Liver Int. 2013. PMID: 23998390
Regulation of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase expression by Zingiber officinale in the liver of high-fat diet-fed rats.
Nammi S, Kim MS, Gavande NS, Li GQ, Roufogalis BD. Nammi S, et al. Basic Clin Pharmacol Toxicol. 2010 May;106(5):389-95. doi: 10.1111/j.1742-7843.2009.00497.x. Epub 2009 Dec 7. Basic Clin Pharmacol Toxicol. 2010. PMID: 20002065
Novel PPAR-gamma agonists identified from a natural product library: a virtual screening, induced-fit docking and biological assay study.
Salam NK, Huang TH, Kota BP, Kim MS, Li Y, Hibbs DE. Salam NK, et al. Chem Biol Drug Des. 2008 Jan;71(1):57-70. doi: 10.1111/j.1747-0285.2007.00606.x. Epub 2007 Dec 18. Chem Biol Drug Des. 2008. PMID: 18086153
7-Hydroxy-benzopyran-4-one derivatives: a novel pharmacophore of peroxisome proliferator-activated receptor alpha and -gamma (PPARalpha and gamma) dual agonists.
Matin A, Gavande N, Kim MS, Yang NX, Salam NK, Hanrahan JR, Roubin RH, Hibbs DE. Matin A, et al. J Med Chem. 2009 Nov 12;52(21):6835-50. doi: 10.1021/jm900964r. J Med Chem. 2009. PMID: 19807106
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