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Transcription as a source of genome instability.
Kim N, Jinks-Robertson S. Kim N, et al. Nat Rev Genet. 2012 Feb 14;13(3):204-14. doi: 10.1038/nrg3152. Nat Rev Genet. 2012. PMID: 22330764 Free PMC article. Review.
The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription.
Michael N, Shen HM, Longerich S, Kim N, Longacre A, Storb U. Michael N, et al. Among authors: kim n. Immunity. 2003 Aug;19(2):235-42. doi: 10.1016/s1074-7613(03)00204-8. Immunity. 2003. PMID: 12932357
Transcription-associated mutagenesis in yeast is directly proportional to the level of gene expression and influenced by the direction of DNA replication.
Kim N, Abdulovic AL, Gealy R, Lippert MJ, Jinks-Robertson S. Kim N, et al. DNA Repair (Amst). 2007 Sep 1;6(9):1285-96. doi: 10.1016/j.dnarep.2007.02.023. Epub 2007 Mar 29. DNA Repair (Amst). 2007. PMID: 17398168 Free PMC article.
dUTP incorporation into genomic DNA is linked to transcription in yeast.
Kim N, Jinks-Robertson S. Kim N, et al. Nature. 2009 Jun 25;459(7250):1150-3. doi: 10.1038/nature08033. Epub 2009 May 17. Nature. 2009. PMID: 19448611 Free PMC article.
Abasic sites in the transcribed strand of yeast DNA are removed by transcription-coupled nucleotide excision repair.
Kim N, Jinks-Robertson S. Kim N, et al. Mol Cell Biol. 2010 Jul;30(13):3206-15. doi: 10.1128/MCB.00308-10. Epub 2010 Apr 26. Mol Cell Biol. 2010. PMID: 20421413 Free PMC article.
Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I.
Kim N, Huang SN, Williams JS, Li YC, Clark AB, Cho JE, Kunkel TA, Pommier Y, Jinks-Robertson S. Kim N, et al. Science. 2011 Jun 24;332(6037):1561-4. doi: 10.1126/science.1205016. Science. 2011. PMID: 21700875 Free PMC article.
Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast.
Kim N, Jinks-Robertson S. Kim N, et al. DNA Repair (Amst). 2011 Sep 5;10(9):953-60. doi: 10.1016/j.dnarep.2011.07.002. Epub 2011 Aug 2. DNA Repair (Amst). 2011. PMID: 21813340 Free PMC article.
The dCMP transferase activity of yeast Rev1 is biologically relevant during the bypass of endogenously generated AP sites.
Kim N, Mudrak SV, Jinks-Robertson S. Kim N, et al. DNA Repair (Amst). 2011 Dec 10;10(12):1262-71. doi: 10.1016/j.dnarep.2011.09.017. Epub 2011 Oct 22. DNA Repair (Amst). 2011. PMID: 22024240 Free PMC article.
Two distinct mechanisms of Topoisomerase 1-dependent mutagenesis in yeast.
Cho JE, Kim N, Li YC, Jinks-Robertson S. Cho JE, et al. Among authors: kim n. DNA Repair (Amst). 2013 Mar 1;12(3):205-11. doi: 10.1016/j.dnarep.2012.12.004. Epub 2013 Jan 8. DNA Repair (Amst). 2013. PMID: 23305949 Free PMC article.
RNA‚ą∂DNA hybrids initiate quasi-palindrome-associated mutations in highly transcribed yeast DNA.
Kim N, Cho JE, Li YC, Jinks-Robertson S. Kim N, et al. PLoS Genet. 2013 Nov;9(11):e1003924. doi: 10.1371/journal.pgen.1003924. Epub 2013 Nov 7. PLoS Genet. 2013. PMID: 24244191 Free PMC article.
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