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The antirheumatic drug leflunomide inhibits osteoclastogenesis by interfering with receptor activator of NF-kappa B ligand-stimulated induction of nuclear factor of activated T cells c1.
Urushibara M, Takayanagi H, Koga T, Kim S, Isobe M, Morishita Y, Nakagawa T, Löeffler M, Kodama T, Kurosawa H, Taniguchi T. Urushibara M, et al. Among authors: kim s. Arthritis Rheum. 2004 Mar;50(3):794-804. doi: 10.1002/art.20206. Arthritis Rheum. 2004. PMID: 15022321
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