Abstract
A new stilbenoid (1) was isolated from the root extract of Polygonum multiflorum together with eight known constituents (2-9). The chemical structure of 1 was established as the 6''-O-monogalloyl ester of (E)-2,3,4',5-beta-tetrahydroxystilbene-2-beta-D-glucopyranoside based on physicochemical and spectroscopic analyses, particularly by NMR spectroscopic data, i.e., COSY, HMQC and HMBC. Compound 1 weakly inhibited acetylcholinesterase in vitro.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetylcholinesterase / chemistry
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Chemistry, Physical
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Cholinesterase Inhibitors / isolation & purification*
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Cholinesterase Inhibitors / pharmacology*
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Magnetic Resonance Spectroscopy
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Molecular Weight
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Plant Roots / chemistry
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Polygonum / chemistry*
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Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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Spectrophotometry, Ultraviolet
Substances
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Cholinesterase Inhibitors
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Acetylcholinesterase