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The major polypeptide of scrapie-associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (PrP).
Hope J, Morton LJ, Farquhar CF, Multhaup G, Beyreuther K, Kimberlin RH. Hope J, et al. Among authors: kimberlin rh. EMBO J. 1986 Oct;5(10):2591-7. EMBO J. 1986. PMID: 3096712 Free PMC article.
Molecular pathology of scrapie-associated fibril protein (PrP) in mouse brain affected by the ME7 strain of scrapie.
Hope J, Multhaup G, Reekie LJ, Kimberlin RH, Beyreuther K. Hope J, et al. Among authors: kimberlin rh. Eur J Biochem. 1988 Mar 1;172(2):271-7. doi: 10.1111/j.1432-1033.1988.tb13883.x. Eur J Biochem. 1988. PMID: 2894984
Scrapie infectivity, fibrils and low molecular weight protein.
Diringer H, Gelderblom H, Hilmert H, Ozel M, Edelbluth C, Kimberlin RH. Diringer H, et al. Among authors: kimberlin rh. Nature. 1983 Dec 1-7;306(5942):476-8. doi: 10.1038/306476a0. Nature. 1983. PMID: 6685822
Scrapie: how much do we really understand?
Kimberlin RH. Kimberlin RH. Neuropathol Appl Neurobiol. 1986 Mar-Apr;12(2):131-47. doi: 10.1111/j.1365-2990.1986.tb00046.x. Neuropathol Appl Neurobiol. 1986. PMID: 2872607
Scrapie-infected spleens: analysis of infectivity, scrapie-associated fibrils, and protease-resistant proteins.
Rubenstein R, Merz PA, Kascsak RJ, Scalici CL, Papini MC, Carp RI, Kimberlin RH. Rubenstein R, et al. Among authors: kimberlin rh. J Infect Dis. 1991 Jul;164(1):29-35. doi: 10.1093/infdis/164.1.29. J Infect Dis. 1991. PMID: 1676044
Introduction to scrapie and perspectives on current scrapie research.
Kimberlin RH. Kimberlin RH. Prog Clin Biol Res. 1989;317:559-66. Prog Clin Biol Res. 1989. PMID: 2574870 Review.
Pathogenesis of experimental scrapie.
Kimberlin RH, Walker CA. Kimberlin RH, et al. Ciba Found Symp. 1988;135:37-62. doi: 10.1002/9780470513613.ch4. Ciba Found Symp. 1988. PMID: 3137002 Review.
Bovine spongiform encephalopathy. Taking stock of the issues.
Kimberlin RH. Kimberlin RH. Nature. 1990 Jun 28;345(6278):763-4. doi: 10.1038/345763a0. Nature. 1990. PMID: 2359452 No abstract available.
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