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Sphingosine enhances apoptosis of radiation-resistant prostate cancer cells.
Nava VE, Cuvillier O, Edsall LC, Kimura K, Milstien S, Gelmann EP, Spiegel S. Nava VE, et al. Among authors: kimura k. Cancer Res. 2000 Aug 15;60(16):4468-74. Cancer Res. 2000. PMID: 10969794
Although LNCaP cells are highly resistant to gamma-irradiation-induced apoptosis, they are sensitive to the death-inducing effects of tumor necrosis factor alpha, which also increases ceramide levels in these cells (K. Kimura et al., Cancer Res., 59: 1606-1614, 1999 …
Although LNCaP cells are highly resistant to gamma-irradiation-induced apoptosis, they are sensitive to the death-inducing effects of tumor …
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