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PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria.
Okatsu K, Oka T, Iguchi M, Imamura K, Kosako H, Tani N, Kimura M, Go E, Koyano F, Funayama M, Shiba-Fukushima K, Sato S, Shimizu H, Fukunaga Y, Taniguchi H, Komatsu M, Hattori N, Mihara K, Tanaka K, Matsuda N. Okatsu K, et al. Among authors: kimura m. Nat Commun. 2012;3:1016. doi: 10.1038/ncomms2016. Nat Commun. 2012. PMID: 22910362 Free PMC article.
Phosphorylated ubiquitin chain is the genuine Parkin receptor.
Okatsu K, Koyano F, Kimura M, Kosako H, Saeki Y, Tanaka K, Matsuda N. Okatsu K, et al. Among authors: kimura m. J Cell Biol. 2015 Apr 13;209(1):111-28. doi: 10.1083/jcb.201410050. Epub 2015 Apr 6. J Cell Biol. 2015. PMID: 25847540 Free PMC article.
6,532 results