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Tubulin and CRMP-2 complex is transported via Kinesin-1.
Kimura T, Watanabe H, Iwamatsu A, Kaibuchi K. Kimura T, et al. J Neurochem. 2005 Jun;93(6):1371-82. doi: 10.1111/j.1471-4159.2005.03063.x. J Neurochem. 2005. PMID: 15935053
CRMP-2 binds to tubulin heterodimers to promote microtubule assembly.
Fukata Y, Itoh TJ, Kimura T, Ménager C, Nishimura T, Shiromizu T, Watanabe H, Inagaki N, Iwamatsu A, Hotani H, Kaibuchi K. Fukata Y, et al. Among authors: kimura t. Nat Cell Biol. 2002 Aug;4(8):583-91. doi: 10.1038/ncb825. Nat Cell Biol. 2002. PMID: 12134159
Axon specification in hippocampal neurons.
Fukata Y, Kimura T, Kaibuchi K. Fukata Y, et al. Among authors: kimura t. Neurosci Res. 2002 Aug;43(4):305-15. doi: 10.1016/s0168-0102(02)00062-7. Neurosci Res. 2002. PMID: 12135774 Review.
Anterograde transport of TrkB in axons is mediated by direct interaction with Slp1 and Rab27.
Arimura N, Kimura T, Nakamuta S, Taya S, Funahashi Y, Hattori A, Shimada A, Ménager C, Kawabata S, Fujii K, Iwamatsu A, Segal RA, Fukuda M, Kaibuchi K. Arimura N, et al. Among authors: kimura t. Dev Cell. 2009 May;16(5):675-86. doi: 10.1016/j.devcel.2009.03.005. Dev Cell. 2009. PMID: 19460344
CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity.
Arimura N, Hattori A, Kimura T, Nakamuta S, Funahashi Y, Hirotsune S, Furuta K, Urano T, Toyoshima YY, Kaibuchi K. Arimura N, et al. Among authors: kimura t. J Neurochem. 2009 Oct;111(2):380-90. doi: 10.1111/j.1471-4159.2009.06317.x. Epub 2009 Jul 31. J Neurochem. 2009. PMID: 19659462
PI3K regulates endocytosis after insulin secretion by mediating signaling crosstalk between Arf6 and Rab27a.
Yamaoka M, Ando T, Terabayashi T, Okamoto M, Takei M, Nishioka T, Kaibuchi K, Matsunaga K, Ishizaki R, Izumi T, Niki I, Ishizaki T, Kimura T. Yamaoka M, et al. Among authors: kimura t. J Cell Sci. 2016 Feb 1;129(3):637-49. doi: 10.1242/jcs.180141. Epub 2015 Dec 18. J Cell Sci. 2016. PMID: 26683831
The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines.
Kimura T, Kaneko Y, Yamada S, Ishihara H, Senda T, Iwamatsu A, Niki I. Kimura T, et al. J Cell Sci. 2008 Sep 15;121(Pt 18):3092-8. doi: 10.1242/jcs.030544. J Cell Sci. 2008. PMID: 18768935
Overexpression of calmodulin in pancreatic beta cells induces diabetic nephropathy.
Yuzawa Y, Niki I, Kosugi T, Maruyama S, Yoshida F, Takeda M, Tagawa Y, Kaneko Y, Kimura T, Kato N, Yamamoto J, Sato W, Nakagawa T, Matsuo S. Yuzawa Y, et al. Among authors: kimura t. J Am Soc Nephrol. 2008 Sep;19(9):1701-11. doi: 10.1681/ASN.2006121358. Epub 2008 Jun 4. J Am Soc Nephrol. 2008. PMID: 18525005 Free PMC article.
Activated Cdc42-bound IQGAP1 determines the cellular endocytic site.
Kimura T, Yamaoka M, Taniguchi S, Okamoto M, Takei M, Ando T, Iwamatsu A, Watanabe T, Kaibuchi K, Ishizaki T, Niki I. Kimura T, et al. Mol Cell Biol. 2013 Dec;33(24):4834-43. doi: 10.1128/MCB.00895-13. Epub 2013 Oct 7. Mol Cell Biol. 2013. PMID: 24100016 Free PMC article.
Actin assembly controlled by GDP-Rab27a is essential for endocytosis of the insulin secretory membrane.
Kimura T, Taniguchi S, Niki I. Kimura T, et al. Arch Biochem Biophys. 2010 Apr 1;496(1):33-7. doi: 10.1016/ Epub 2010 Feb 4. Arch Biochem Biophys. 2010. PMID: 20138020
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