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RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1.
Katagiri K, Maeda A, Shimonaka M, Kinashi T. Katagiri K, et al. Among authors: kinashi t. Nat Immunol. 2003 Aug;4(8):741-8. doi: 10.1038/ni950. Epub 2003 Jul 6. Nat Immunol. 2003. PMID: 12845325
Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses.
Katagiri K, Hattori M, Minato N, Kinashi T. Katagiri K, et al. Among authors: kinashi t. Mol Cell Biol. 2002 Feb;22(4):1001-15. doi: 10.1128/mcb.22.4.1001-1015.2002. Mol Cell Biol. 2002. PMID: 11809793 Free PMC article.
[Regulation of integrin-mediated adhesion and migration by Rap1].
Kinashi T. Kinashi T. Tanpakushitsu Kakusan Koso. 2002 Dec;47(16 Suppl):2200-5. Tanpakushitsu Kakusan Koso. 2002. PMID: 12518437 Review. Japanese. No abstract available.
Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow.
Shimonaka M, Katagiri K, Nakayama T, Fujita N, Tsuruo T, Yoshie O, Kinashi T. Shimonaka M, et al. Among authors: kinashi t. J Cell Biol. 2003 Apr 28;161(2):417-27. doi: 10.1083/jcb.200301133. Epub 2003 Apr 21. J Cell Biol. 2003. PMID: 12707305 Free PMC article.
Thromboxane A2 modulates interaction of dendritic cells and T cells and regulates acquired immunity.
Kabashima K, Murata T, Tanaka H, Matsuoka T, Sakata D, Yoshida N, Katagiri K, Kinashi T, Tanaka T, Miyasaka M, Nagai H, Ushikubi F, Narumiya S. Kabashima K, et al. Among authors: kinashi t. Nat Immunol. 2003 Jul;4(7):694-701. doi: 10.1038/ni943. Epub 2003 Jun 1. Nat Immunol. 2003. PMID: 12778172
The critical cytoplasmic regions of the alphaL/beta2 integrin in Rap1-induced adhesion and migration.
Tohyama Y, Katagiri K, Pardi R, Lu C, Springer TA, Kinashi T. Tohyama Y, et al. Among authors: kinashi t. Mol Biol Cell. 2003 Jun;14(6):2570-82. doi: 10.1091/mbc.e02-09-0615. Epub 2003 Mar 7. Mol Biol Cell. 2003. PMID: 12808052 Free PMC article.
LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds.
Kinashi T, Aker M, Sokolovsky-Eisenberg M, Grabovsky V, Tanaka C, Shamri R, Feigelson S, Etzioni A, Alon R. Kinashi T, et al. Blood. 2004 Feb 1;103(3):1033-6. doi: 10.1182/blood-2003-07-2499. Epub 2003 Oct 9. Blood. 2004. PMID: 14551137
Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1.
Katagiri K, Shimonaka M, Kinashi T. Katagiri K, et al. Among authors: kinashi t. J Biol Chem. 2004 Mar 19;279(12):11875-81. doi: 10.1074/jbc.M310717200. Epub 2003 Dec 31. J Biol Chem. 2004. PMID: 14702343
Regulation of lymphocyte adhesion and migration by the small GTPase Rap1 and its effector molecule, RAPL.
Kinashi T, Katagiri K. Kinashi T, et al. Immunol Lett. 2004 Apr 30;93(1):1-5. doi: 10.1016/j.imlet.2004.02.008. Immunol Lett. 2004. PMID: 15134891 Review.
Aquaporin-2 trafficking is regulated by PDZ-domain containing protein SPA-1.
Noda Y, Horikawa S, Furukawa T, Hirai K, Katayama Y, Asai T, Kuwahara M, Katagiri K, Kinashi T, Hattori M, Minato N, Sasaki S. Noda Y, et al. Among authors: kinashi t. FEBS Lett. 2004 Jun 18;568(1-3):139-45. doi: 10.1016/j.febslet.2004.05.021. FEBS Lett. 2004. PMID: 15196935
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