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Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus.
Lundin A, Dijkman R, Bergström T, Kann N, Adamiak B, Hannoun C, Kindler E, Jónsdóttir HR, Muth D, Kint J, Forlenza M, Müller MA, Drosten C, Thiel V, Trybala E. Lundin A, et al. Among authors: kindler e. PLoS Pathog. 2014 May 29;10(5):e1004166. doi: 10.1371/journal.ppat.1004166. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24874215 Free PMC article.
SARS-CoV and IFN: Too Little, Too Late.
Kindler E, Thiel V. Kindler E, et al. Cell Host Microbe. 2016 Feb 10;19(2):139-41. doi: 10.1016/j.chom.2016.01.012. Cell Host Microbe. 2016. PMID: 26867172 Free PMC article.
APOBEC3-mediated restriction of RNA virus replication.
Milewska A, Kindler E, Vkovski P, Zeglen S, Ochman M, Thiel V, Rajfur Z, Pyrc K. Milewska A, et al. Among authors: kindler e. Sci Rep. 2018 Apr 13;8(1):5960. doi: 10.1038/s41598-018-24448-2. Sci Rep. 2018. PMID: 29654310 Free PMC article.
Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication.
Kindler E, Gil-Cruz C, Spanier J, Li Y, Wilhelm J, Rabouw HH, Züst R, Hwang M, V'kovski P, Stalder H, Marti S, Habjan M, Cervantes-Barragan L, Elliot R, Karl N, Gaughan C, van Kuppeveld FJ, Silverman RH, Keller M, Ludewig B, Bergmann CC, Ziebuhr J, Weiss SR, Kalinke U, Thiel V. Kindler E, et al. PLoS Pathog. 2017 Feb 3;13(2):e1006195. doi: 10.1371/journal.ppat.1006195. eCollection 2017 Feb. PLoS Pathog. 2017. PMID: 28158275 Free PMC article.
Sequestration by IFIT1 impairs translation of 2'O-unmethylated capped RNA.
Habjan M, Hubel P, Lacerda L, Benda C, Holze C, Eberl CH, Mann A, Kindler E, Gil-Cruz C, Ziebuhr J, Thiel V, Pichlmair A. Habjan M, et al. Among authors: kindler e. PLoS Pathog. 2013;9(10):e1003663. doi: 10.1371/journal.ppat.1003663. Epub 2013 Oct 3. PLoS Pathog. 2013. PMID: 24098121 Free PMC article.
39 results